ID   TUBE_BPF41              Reviewed;         301 AA.
AC   P26596;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   12-AUG-2020, entry version 47.
DE   RecName: Full=Tail tube protein {ECO:0000250|UniProtKB:Q9MCC1};
DE            Short=TTP;
DE   AltName: Full=Major tail protein {ECO:0000250|UniProtKB:Q9MCC1};
DE            Short=MTP {ECO:0000250|UniProtKB:Q9MCC1};
OS   Lactococcus phage F4-1 (Lactococcus lactis bacteriophage F4-1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Skunavirus; unclassified Skunavirus.
OX   NCBI_TaxID=12387;
OH   NCBI_TaxID=1358; Lactococcus lactis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-13.
RX   PubMed=1905665; DOI=10.1016/0378-1119(91)90233-2;
RA   Chung D.K., Kim J.H., Batt C.A.;
RT   "Cloning and nucleotide sequence of the major capsid protein from
RT   Lactococcus lactis ssp. cremoris bacteriophage F4-1.";
RL   Gene 101:121-125(1991).
CC   -!- FUNCTION: Forms the cylindrical rigid tail tube.
CC       {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SUBUNIT: Homohexamer. The tube is composed of 31 hexameric rings.
CC       {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SIMILARITY: Belongs to the skunalikevirus tail tube protein family.
CC       {ECO:0000305}.
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DR   EMBL; M37979; AAA66055.1; -; Genomic_DNA.
DR   PIR; JE0412; VHBPLL.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0098026; C:virus tail, tube; IEA:UniProtKB-KW.
DR   GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR010517; L_lac_phage_MSP.
DR   Pfam; PF06488; L_lac_phage_MSP; 1.
DR   PIRSF; PIRSF004357; L_lac_phage_MSP; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Direct protein sequencing;
KW   Viral genome ejection through host cell envelope;
KW   Viral long flexible tail ejection system;
KW   Viral penetration into host cytoplasm; Viral tail protein;
KW   Viral tail tube protein; Virion; Virus entry into host cell.
FT   CHAIN           1..301
FT                   /note="Tail tube protein"
FT                   /id="PRO_0000096303"
SQ   SEQUENCE   301 AA;  32389 MW;  B0D65D6F0107E4FF CRC64;
     MKLDYNSREI FFGNEALIVA DMSKGINGKP EFTNHKIVAG LVSVGSMEDQ AETNSYPADD
     VPDHGVKKGA TLLQGEMVFI QTDQALKEDI LGQQRTENGL GWSPTGNWKT KCVQYLIKGR
     KRDKVTGEFV DGYRVVVYPN LTPTAEATKE SETDSVDGVD PIQWTLAVQA TESDIYLNGG
     KKVPAIEYEI WGEQAKDFVK KMESGLFIMQ PDTVLAGAIT LVAPVIPNVT TATKGNNDGT
     IVVPDTLKDS KGGTVKVTSV IKDAHGKVAT NGQLAPGVYI VTFSADGYED VTAGVSVTDH
     S