ID   TUBE_BPLSK              Reviewed;         301 AA.
AC   O21879;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   23-FEB-2022, entry version 50.
DE   RecName: Full=Tail tube protein {ECO:0000250|UniProtKB:Q9MCC1};
DE            Short=TTP;
DE   AltName: Full=Gene product 11 {ECO:0000305};
DE            Short=gp11 {ECO:0000305};
DE   AltName: Full=Major tail protein {ECO:0000250|UniProtKB:Q9MCC1};
DE            Short=MTP {ECO:0000250|UniProtKB:Q9MCC1};
OS   Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Skunavirus.
OX   NCBI_TaxID=31532;
OH   NCBI_TaxID=1358; Lactococcus lactis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9383189; DOI=10.1046/j.1365-2958.1997.5491926.x;
RA   Chandry P.S., Moore S.C., Boyce J.D., Davidson B.E., Hillier A.J.;
RT   "Analysis of the DNA sequence, gene expression, origin of replication and
RT   modular structure of the Lactococcus lactis lytic bacteriophage sk1.";
RL   Mol. Microbiol. 26:49-64(1997).
CC   -!- FUNCTION: Forms the cylindrical rigid tail tube with a 4 nm wide
CC       central channel for DNA ejection. The tube is composed of 31 hexameric
CC       rings. {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SUBUNIT: Homohexamer. Interacts with the tail terminator protein.
CC       {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q9MCC1}.
CC       Note=Constitutes the tail tube. {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- DOMAIN: The C-terminus probably makes protruding decorations on the
CC       whole length of the tail tube. {ECO:0000250|UniProtKB:Q9MCC1}.
CC   -!- SIMILARITY: Belongs to the skunalikevirus tail tube protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF011378; AAB70050.1; -; Genomic_DNA.
DR   RefSeq; NP_044957.1; NC_001835.1.
DR   GeneID; 1261264; -.
DR   KEGG; vg:1261264; -.
DR   Proteomes; UP000000839; Genome.
DR   GO; GO:0098026; C:virus tail, tube; IEA:UniProtKB-KW.
DR   GO; GO:0099001; P:viral genome ejection through host cell envelope, long flexible tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR010517; L_lac_phage_MSP.
DR   Pfam; PF06488; L_lac_phage_MSP; 1.
DR   PIRSF; PIRSF004357; L_lac_phage_MSP; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Viral genome ejection through host cell envelope;
KW   Viral long flexible tail ejection system;
KW   Viral penetration into host cytoplasm; Viral tail protein;
KW   Viral tail tube protein; Virion; Virus entry into host cell.
FT   CHAIN           1..301
FT                   /note="Tail tube protein"
FT                   /id="PRO_0000438253"
SQ   SEQUENCE   301 AA;  32332 MW;  95D66B32CBC8BA06 CRC64;
     MKLDYNSREI FFGNEALIVA DMTKGSNGKP EFTNHKIVTG LVSVGSMEDQ AETNSYPADD
     VPDHGVKKGA TLLQGEMVFI QTDQALKEDI LGQQRTENGL GWSPTGNWKT KCVQYLIKGR
     KRDKVTGEFV DGYRVVVYPH LTPTAEATKE SETDSVDGVD PIQWTLAVQA TDSDIYSNGG
     KKVPAIEYEI WGEQAKDFAK KMESGLFIMQ PDTVLAGAIT LVAPVIPNVT TATKGNNDGT
     IVVPATLKDS KGGTIKVTSV IKDAHGKVAT NGQLAPGVYI VTFSADGYED VTAGVSVTDH
     S