ID   TUBE_MYCTX              Reviewed;          89 AA.
AC   P02944;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Tuberculin-active protein;
OS   Mycobacterium tuberculosis.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=1773;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=Human type Aoyama/B;
RX   PubMed=804477; DOI=10.1016/s0021-9258(19)41637-2;
RA   Kuwabara S.;
RT   "Amino acid sequence of tuberculin-active protein from Mycobacterium
RT   tuberculosis.";
RL   J. Biol. Chem. 250:2563-2568(1975).
CC   -!- FUNCTION: Tuberculin is the soluble, proteinaceous cell substance of
CC       the bacterium, to which infected animals become hypersensitive and
CC       react characteristically to dermal injections.
CC   -!- MISCELLANEOUS: This protein is the most potent component with
CC       tuberculin activity so far purified and characterized.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A03444; TKMYT.
DR   AlphaFoldDB; P02944; -.
DR   InterPro; IPR022015; Tuberculin.
DR   Pfam; PF12198; Tuberculin; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond.
FT   CHAIN           1..89
FT                   /note="Tuberculin-active protein"
FT                   /id="PRO_0000065696"
FT   REGION          61..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        27..59
FT                   /evidence="ECO:0000269|PubMed:804477"
SQ   SEQUENCE   89 AA;  9494 MW;  91DA5E8B044660F1 CRC64;
     RLLDDTPEVK VLGAVADAIE TPKAEPCIDL DVAGEATFAR EDDLPDYVLY AEVTFHEICR
     DGGSESEGKN GSQMRLIADV GPESATVAK