ID   TULP1_CULQU             Reviewed;         427 AA.
AC   B0XFQ9;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Protein king tubby 1;
GN   Name=king-tubby1; ORFNames=CPIJ017614;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000312|EMBL:EDS26940.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000312|EMBL:EDS26940.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86PC9}. Nucleus
CC       {ECO:0000250|UniProtKB:Q86PC9}.
CC   -!- SIMILARITY: Belongs to the TUB family. {ECO:0000255}.
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DR   EMBL; DS232951; EDS26940.1; -; Genomic_DNA.
DR   RefSeq; XP_001868481.1; XM_001868446.1.
DR   AlphaFoldDB; B0XFQ9; -.
DR   SMR; B0XFQ9; -.
DR   STRING; 7176.CPIJ017614-PA; -.
DR   GeneID; 6052171; -.
DR   KEGG; cqu:CpipJ_CPIJ017614; -.
DR   VEuPathDB; VectorBase:CPIJ017614; -.
DR   VEuPathDB; VectorBase:CQUJHB007753; -.
DR   eggNOG; KOG2502; Eukaryota.
DR   HOGENOM; CLU_028236_1_1_1; -.
DR   InParanoid; B0XFQ9; -.
DR   OMA; GYDGPMQ; -.
DR   OrthoDB; 1445357at2759; -.
DR   PhylomeDB; B0XFQ9; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   Gene3D; 3.20.90.10; -; 1.
DR   InterPro; IPR025659; Tubby-like_C.
DR   InterPro; IPR000007; Tubby_C.
DR   InterPro; IPR018066; Tubby_C_CS.
DR   Pfam; PF01167; Tub; 1.
DR   PRINTS; PR01573; SUPERTUBBY.
DR   SUPFAM; SSF54518; SSF54518; 1.
DR   PROSITE; PS01200; TUB_1; 1.
DR   PROSITE; PS01201; TUB_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..427
FT                   /note="Protein king tubby 1"
FT                   /id="PRO_0000400831"
FT   REGION          48..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..97
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   427 AA;  47119 MW;  01D0D2AA2550E198 CRC64;
     MEAYIRQKRA TPGMVQASDL QLVRPMSAVN RNGREVHAYD GPMQFMMSPS NPDQIISSSG
     SPTTVTATGT GTTTTTGSVT TTPTSPYSDA TLEKLTPSSQ DSEDEESTPV DILPSSNSFD
     RHSDGHLTHS APISPALNNN VSRDSQQDSG SSGNLKSMEH SSPQASGHND AEGDVAGPIE
     QWVTQPAAQG VLYKCRITRD RKGMDRGLFP IYYLHLERDY GKRLFCLAGR KRKKSKTSNY
     IISCDPTDLS RQADGFVGKL RSNVFGTTFF VYDNGKKDDP VSPRLDLAVV IYDTNILGFK
     GPRNMTVLLP GMTEDDQRVK INSSDSHGQG LLDSWKSKHM DNVVELHNKT PIWNDETQSY
     VLNFHGRVTQ ASVKNFQLVH DSDPDYIVMQ FGRTSDDIFT MDFRYPLCAF QAFAIALSSF
     DGKLACE