ID   TULP2_CULQU             Reviewed;         422 AA.
AC   B0WI30;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 2.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Protein king tubby 2;
GN   Name=king-tubby2; ORFNames=CPIJ006491;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000312|EMBL:EDS28112.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000312|EMBL:EDS28112.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86PC9}. Nucleus
CC       {ECO:0000250|UniProtKB:Q86PC9}.
CC   -!- SIMILARITY: Belongs to the TUB family. {ECO:0000255}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDS28112.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS231941; EDS28112.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001848364.1; XM_001848312.1.
DR   AlphaFoldDB; B0WI30; -.
DR   SMR; B0WI30; -.
DR   STRING; 7176.CPIJ006491-PA; -.
DR   KEGG; cqu:CpipJ_CPIJ006491; -.
DR   VEuPathDB; VectorBase:CPIJ017614; -.
DR   VEuPathDB; VectorBase:CQUJHB007753; -.
DR   HOGENOM; CLU_028236_1_1_1; -.
DR   InParanoid; B0WI30; -.
DR   OrthoDB; 1445357at2759; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   Gene3D; 3.20.90.10; -; 1.
DR   InterPro; IPR025659; Tubby-like_C.
DR   InterPro; IPR000007; Tubby_C.
DR   InterPro; IPR018066; Tubby_C_CS.
DR   Pfam; PF01167; Tub; 1.
DR   PRINTS; PR01573; SUPERTUBBY.
DR   SUPFAM; SSF54518; SSF54518; 1.
DR   PROSITE; PS01200; TUB_1; 1.
DR   PROSITE; PS01201; TUB_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..422
FT                   /note="Protein king tubby 2"
FT                   /id="PRO_0000400833"
FT   REGION          49..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..163
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   422 AA;  46672 MW;  D33C0BE0F530BE30 CRC64;
     MEAYIRQKRA TPGMVQASDL QLVRPMSAVN RNGREVHAYD GPMQFMMSPS NPDQIISSGS
     PTTVTATGTT TGSVTTTPTS PYSDATLEKL TPSSQDSEDE ESTPVDILPS SNSFDRHSDG
     HLTHSAPISP ALNNNVSRDS QQDSGSSGNL KSMEHSSPQA SGHNDAEGDV AGPIEQWVTQ
     PAAQGVLYKC RITRDRKGMD RGLFPIYYLH LERDYGKRLF CLAGRKRKKS KTSNYIISCD
     PTDLSRQADG FVGKLRSNVF GTTFFVYDNG KKDDPVSPRL DLAVVIYDTN ILGFKGPRNM
     TVLLPGMTED DQRVKINSSD SHGQGLLDSW KSKHMDNVVE LHNKTPIWND ETQSYVLNFH
     GRVTQASVKN FQLVHDSDPD YIVMQFGRTS DDIFTMDFRY PLCAFQAFAI ALSSFDGKLA
     CE