ID   TULP_DROAN              Reviewed;         449 AA.
AC   B3MDU3;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Protein king tubby {ECO:0000250|UniProtKB:Q86PC9};
GN   Name=king-tubby {ECO:0000250|UniProtKB:Q86PC9}; ORFNames=GF11934;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1] {ECO:0000312|EMBL:EDV36478.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13 {ECO:0000312|EMBL:EDV36478.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86PC9}. Nucleus
CC       {ECO:0000250|UniProtKB:Q86PC9}.
CC   -!- SIMILARITY: Belongs to the TUB family. {ECO:0000255}.
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DR   EMBL; CH902619; EDV36478.1; -; Genomic_DNA.
DR   RefSeq; XP_001959656.2; XM_001959620.2.
DR   AlphaFoldDB; B3MDU3; -.
DR   SMR; B3MDU3; -.
DR   STRING; 7217.FBpp0115126; -.
DR   PRIDE; B3MDU3; -.
DR   GeneID; 6494793; -.
DR   KEGG; dan:6494793; -.
DR   eggNOG; KOG2502; Eukaryota.
DR   HOGENOM; CLU_028236_1_1_1; -.
DR   InParanoid; B3MDU3; -.
DR   OMA; GYDGPMQ; -.
DR   PhylomeDB; B3MDU3; -.
DR   ChiTaRS; ktub; fly.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   Gene3D; 3.20.90.10; -; 1.
DR   InterPro; IPR025659; Tubby-like_C.
DR   InterPro; IPR000007; Tubby_C.
DR   InterPro; IPR018066; Tubby_C_CS.
DR   Pfam; PF01167; Tub; 1.
DR   PRINTS; PR01573; SUPERTUBBY.
DR   SUPFAM; SSF54518; SSF54518; 1.
DR   PROSITE; PS01200; TUB_1; 1.
DR   PROSITE; PS01201; TUB_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..449
FT                   /note="Protein king tubby"
FT                   /id="PRO_0000400835"
FT   REGION          123..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..140
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         142
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q86PC9"
SQ   SEQUENCE   449 AA;  49981 MW;  41937F23C5EAA448 CRC64;
     MGRLERQLME AYIRQKRASP GMVQASDLQI NRPMSGMRSN SRELHAYDGP MQFISSPQNP
     DQILSNGSPG GIAPATINTS RNHSNNMRSL STINQEADLI EEISSHELED EESSPVTVIE
     QHSAVHSANS TQSQRPRPRQ HSFSDTLDED DYTNRNVAAA APVRPAGVPS SPYKEATLDG
     SSNGTGNGTG GESEGDVIGN IDQFVMQPAP QGVLYKCRIT RDRKGMDRGL FPIYYLHLER
     DYGKKIFLLG GRKRKKSKTS NYIVSCDPTD LSRNADGFCG KLRSNVFGTS FTVFDNGNKE
     STESPRLDLA VIIYDTNILG FKGPRNMTVI LPGMTEDDQR VKISSADPKQ QGILDLWKMK
     NMDNIVELHN KTPVWNDETQ SYVLNFHGRV TQASVKNFQL VHDSDPEYIV MQFGRTSEDV
     FTMDYRYPLC AMQAFAIALS SFDGKIACE