TULP_DROMO
ID TULP_DROMO Reviewed; 453 AA.
AC B4KNA9;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Protein king tubby {ECO:0000250|UniProtKB:Q86PC9};
GN Name=king-tubby {ECO:0000250|UniProtKB:Q86PC9}; ORFNames=GI20804;
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230;
RN [1] {ECO:0000312|EMBL:EDW09962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15081-1352.22 {ECO:0000312|EMBL:EDW09962.1};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q86PC9}. Nucleus
CC {ECO:0000250|UniProtKB:Q86PC9}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000255}.
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DR EMBL; CH933808; EDW09962.1; -; Genomic_DNA.
DR RefSeq; XP_002006027.2; XM_002005991.2.
DR RefSeq; XP_015019612.1; XM_015164126.1.
DR RefSeq; XP_015019613.1; XM_015164127.1.
DR RefSeq; XP_015019614.1; XM_015164128.1.
DR AlphaFoldDB; B4KNA9; -.
DR SMR; B4KNA9; -.
DR STRING; 7230.FBpp0170021; -.
DR EnsemblMetazoa; FBtr0428622; FBpp0386147; FBgn0143539.
DR GeneID; 6580167; -.
DR eggNOG; KOG2502; Eukaryota.
DR HOGENOM; CLU_028236_1_1_1; -.
DR InParanoid; B4KNA9; -.
DR OMA; GYDGPMQ; -.
DR OrthoDB; 1445357at2759; -.
DR PhylomeDB; B4KNA9; -.
DR ChiTaRS; ktub; fly.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR Gene3D; 3.20.90.10; -; 1.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR Pfam; PF01167; Tub; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR SUPFAM; SSF54518; SSF54518; 1.
DR PROSITE; PS01200; TUB_1; 1.
DR PROSITE; PS01201; TUB_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..453
FT /note="Protein king tubby"
FT /id="PRO_0000400839"
FT REGION 19..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 142
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q86PC9"
SQ SEQUENCE 453 AA; 50302 MW; F0DD94B9ADD87D04 CRC64;
MGVTQRQLMD AYIRQKRASP GMVQASDLQM SRPMSGMRSN SRELHGYDGP MQFIGSPHNP
DQILSNNSTT GVHLTSSLNS SRNNSNNLRS LSTINQEDLI EEISSHELED DESSPVTVVE
QPIQPQSANS MQSQRLRSGQ QSFNEPLDED DYANRNISGV AAVRPANIAS PYKDSAAVEG
SNGTANGSGS IGGNGESEGD VIGNIDQFVM QPAPQGVLYK CRITRDRKGM DRGLFPIYYL
HLERDYGKKI FLLGGRKRKK SKTSNYIVSC DPTDLSRNAD GFCGKLRSNV FGTSFTVFDS
GNKESTENPR LDLAVIIYDT NILGFKGPRN MTVILPGMTE DDQRVKISSA DPKQQGILDL
WKMKNMDNIV ELHNKTPVWN DETQSYVLNF HGRVTQASVK NFQLVHDSDP EYIVMQFGRT
SEDVFTMDYR YPLCAMQAFA IALSSFDGKI ACE
