ID   TUM_BP186               Reviewed;         146 AA.
AC   P41063; O80318; O80319;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 3.
DT   07-OCT-2020, entry version 83.
DE   RecName: Full=SOS operon TUM protein;
DE   AltName: Full=ORF95 protein;
DE   AltName: Full=Protein TUM95;
GN   Name=TUM; Synonyms=CP95;
OS   Escherichia phage 186 (Bacteriophage 186).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Peduovirinae; Eganvirus.
OX   NCBI_TaxID=29252;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8623519; DOI=10.1006/viro.1996.0227;
RA   Brumby A.M., Lamont I., Dodd I.B., Egan J.B.;
RT   "Defining the SOS operon of coliphage 186.";
RL   Virology 219:105-114(1996).
RN   [2]
RP   SEQUENCE REVISION TO 132.
RA   Dodd I.B., Egan J.B.;
RT   "Bacteriophage 186 complete genome.";
RL   Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 47-114.
RC   STRAIN=186CITSP;
RX   PubMed=2352277; DOI=10.1016/s0022-2836(05)80207-4;
RA   Sivaprasad A.V., Jarvinen R., Puspurs A., Egan J.B.;
RT   "DNA replication studies with coliphage 186. III. A single phage gene is
RT   required for phage 186 replication.";
RL   J. Mol. Biol. 213:449-463(1990).
CC   -!- FUNCTION: The TUM protein is responsible for UV induction of the 186
CC       prophage. The other three proteins modulate TUM activity.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative initiation; Named isoforms=4;
CC       Name=ORF95.1; Synonyms=TUM95.1;
CC         IsoId=P41063-1; Sequence=Displayed;
CC       Name=ORF95.2; Synonyms=TUM95.2;
CC         IsoId=P41063-2; Sequence=VSP_018713;
CC       Name=ORF95.4; Synonyms=TUM95.4;
CC         IsoId=P41063-3; Sequence=VSP_018714;
CC       Name=ORF95.5; Synonyms=TUM95.5;
CC         IsoId=P41063-4; Sequence=VSP_018715, VSP_018989;
CC   -!- SIMILARITY: Belongs to the dinI family. {ECO:0000305}.
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DR   EMBL; U32222; AAC34187.1; -; Genomic_DNA.
DR   EMBL; U32222; AAC34188.1; -; Genomic_DNA.
DR   EMBL; U32222; AAC34189.1; -; Genomic_DNA.
DR   EMBL; U32222; AAC34190.1; -; Genomic_DNA.
DR   PIR; S10633; S10633.
DR   RefSeq; NP_052290.1; NC_001317.1.
DR   RefSeq; NP_052291.1; NC_001317.1.
DR   RefSeq; NP_052292.1; NC_001317.1.
DR   RefSeq; NP_052293.1; NC_001317.1.
DR   SMR; P41063; -.
DR   GeneID; 1262465; -.
DR   KEGG; vg:1262465; -.
DR   Proteomes; UP000000369; Genome.
DR   Gene3D; 3.30.910.10; -; 1.
DR   InterPro; IPR036687; DinI-like_sf.
DR   InterPro; IPR010391; DNA_damage-inducible_DinI-like.
DR   PANTHER; PTHR36572; PTHR36572; 1.
DR   Pfam; PF06183; DinI; 1.
DR   SUPFAM; SSF54857; SSF54857; 1.
PE   1: Evidence at protein level;
KW   Alternative initiation; Reference proteome.
FT   CHAIN           1..146
FT                   /note="SOS operon TUM protein"
FT                   /id="PRO_0000007232"
FT   VAR_SEQ         1..70
FT                   /note="Missing (in isoform ORF95.5)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018715"
FT   VAR_SEQ         1..46
FT                   /note="Missing (in isoform ORF95.4)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018714"
FT   VAR_SEQ         1..9
FT                   /note="Missing (in isoform ORF95.2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018713"
FT   VAR_SEQ         71
FT                   /note="V -> M (in isoform ORF95.5)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018989"
FT   MUTAGEN         12
FT                   /note="E->K: In TUM16; loss of prophage induction."
FT   MUTAGEN         34
FT                   /note="A->V: In TUM17; loss of prophage induction."
FT   MUTAGEN         40
FT                   /note="E->K: In TUM14; loss of prophage induction."
FT   MUTAGEN         104
FT                   /note="P->S: In TUM2; loss of prophage induction."
SQ   SEQUENCE   146 AA;  16574 MW;  7945E2E0E7E2A17B CRC64;
     MDRELNEHVM IERVEMIARL TAEGTCQERD REIALNLIAE IARGNLMKNN NFSVVFSAPP
     VGETFAKEGK VKVNITLDKD QKIGQPVIDA FQCELTKRIQ SVFPSTRVTV KKGSMTGVEL
     MGFDKDSDRE ALDSILQEVW EDESWR