ID   TUPB_PEPAC              Reviewed;         228 AA.
AC   Q93KD5;
DT   17-FEB-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Tungstate uptake system permease protein TupB {ECO:0000305};
GN   Name=tupB {ECO:0000303|PubMed:11292832};
OS   Peptoclostridium acidaminophilum (Eubacterium acidaminophilum).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC   Peptoclostridium.
OX   NCBI_TaxID=1731;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROBABLE FUNCTION IN TUNGSTATE
RP   UPTAKE.
RC   STRAIN=ATCC 49065 / DSM 3953 / al-2;
RX   PubMed=11292832; DOI=10.1074/jbc.m101293200;
RA   Makdessi K., Andreesen J.R., Pich A.;
RT   "Tungstate uptake by a highly specific ABC transporter in Eubacterium
RT   acidaminophilum.";
RL   J. Biol. Chem. 276:24557-24564(2001).
CC   -!- FUNCTION: Part of an ABC transporter complex involved in tungstate
CC       uptake. Probably responsible for the translocation of the substrate
CC       across the membrane. {ECO:0000305|PubMed:11292832}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (TupC),
CC       two transmembrane proteins (TupB) and a solute-binding protein (TupA).
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
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DR   EMBL; AJ291988; CAC40783.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q93KD5; -.
DR   SMR; Q93KD5; -.
DR   TCDB; 3.A.1.6.2; the atp-binding cassette (abc) superfamily.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..228
FT                   /note="Tungstate uptake system permease protein TupB"
FT                   /id="PRO_0000435510"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          26..222
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   228 AA;  24541 MW;  248F1ED7217F76DF CRC64;
     MEYIAEGFRA AMELLVSFDP QVYTIIFLSV FVSSTATAIA AAVSIPLGIF AGISNFRLKR
     LFSKVLYSLM SVPSVIVGLV VAIGLSRRGP LGFMQLLYTP TAMIIAQALL VFPLCLGLTY
     SLSKNRGSEI ERIGKTLGAG KLQVIILIIR ELKAELFINV VTTFSRAISE VGAVMIVGGN
     IKGHTRVITT SIAMLNSMGD YPMAIALGLV LLMISFAINA VIYSLQEE