TUSE_PECAS
ID TUSE_PECAS Reviewed; 109 AA.
AC Q6D6C3;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Sulfurtransferase TusE;
DE EC=2.8.1.-;
DE AltName: Full=tRNA 2-thiouridine synthesizing protein E;
GN Name=tusE; OrderedLocusNames=ECA1762;
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCRI 1043 / ATCC BAA-672;
RX PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT subsp. atroseptica and characterization of virulence factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC -!- FUNCTION: Part of a sulfur-relay system required for 2-thiolation of 5-
CC methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
CC Could accept sulfur from TusD (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the TusBCD complex. Interacts with MnmA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DsrC/TusE family. {ECO:0000305}.
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DR EMBL; BX950851; CAG74667.1; -; Genomic_DNA.
DR RefSeq; WP_011093338.1; NC_004547.2.
DR AlphaFoldDB; Q6D6C3; -.
DR SMR; Q6D6C3; -.
DR STRING; 218491.ECA1762; -.
DR EnsemblBacteria; CAG74667; CAG74667; ECA1762.
DR GeneID; 57209525; -.
DR KEGG; eca:ECA1762; -.
DR eggNOG; COG2920; Bacteria.
DR HOGENOM; CLU_153199_1_0_6; -.
DR OMA; EYNTSPA; -.
DR OrthoDB; 1840461at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.370; -; 1.
DR Gene3D; 3.30.1420.10; -; 1.
DR InterPro; IPR042072; DsrC-like_C.
DR InterPro; IPR025526; DsrC-like_dom_sf.
DR InterPro; IPR043163; DsrC-like_N.
DR InterPro; IPR007453; DsrC/TusE.
DR PANTHER; PTHR37010; PTHR37010; 1.
DR Pfam; PF04358; DsrC; 1.
DR PIRSF; PIRSF006223; DsrC_TusE; 1.
DR SUPFAM; SSF69721; SSF69721; 1.
DR TIGRFAMs; TIGR03342; dsrC_tusE_dsvC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Transferase; tRNA processing.
FT CHAIN 1..109
FT /note="Sulfurtransferase TusE"
FT /id="PRO_0000234612"
FT ACT_SITE 108
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 109 AA; 12283 MW; 0CC7FF79E6F815D7 CRC64;
MLEFEGRTIA TDAQGYLMDS TAWSEALAPV LAEQEGIALT EPHWEVVRFV RNFYQEFNTS
PAIRMLVKAM AQKYGEEKGN SRYLYKLFPK GPAKQATKIA GLPKPVKCI