TUSE_SALCH
ID TUSE_SALCH Reviewed; 109 AA.
AC Q57QR9;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Sulfurtransferase TusE;
DE EC=2.8.1.-;
DE AltName: Full=tRNA 2-thiouridine synthesizing protein E;
GN Name=tusE; OrderedLocusNames=SCH_1036;
OS Salmonella choleraesuis (strain SC-B67).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=321314;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC-B67;
RX PubMed=15781495; DOI=10.1093/nar/gki297;
RA Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA Lee Y.-S.;
RT "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT invasive and resistant zoonotic pathogen.";
RL Nucleic Acids Res. 33:1690-1698(2005).
CC -!- FUNCTION: Part of a sulfur-relay system required for 2-thiolation of 5-
CC methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
CC Could accept sulfur from TusD (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the TusBCD complex. Interacts with MnmA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DsrC/TusE family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE017220; AAX64942.1; -; Genomic_DNA.
DR RefSeq; WP_001539655.1; NC_006905.1.
DR AlphaFoldDB; Q57QR9; -.
DR SMR; Q57QR9; -.
DR EnsemblBacteria; AAX64942; AAX64942; SCH_1036.
DR KEGG; sec:SCH_1036; -.
DR HOGENOM; CLU_153199_1_0_6; -.
DR OMA; EYNTSPA; -.
DR Proteomes; UP000000538; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.370; -; 1.
DR Gene3D; 3.30.1420.10; -; 1.
DR InterPro; IPR042072; DsrC-like_C.
DR InterPro; IPR025526; DsrC-like_dom_sf.
DR InterPro; IPR043163; DsrC-like_N.
DR InterPro; IPR007453; DsrC/TusE.
DR PANTHER; PTHR37010; PTHR37010; 1.
DR Pfam; PF04358; DsrC; 1.
DR PIRSF; PIRSF006223; DsrC_TusE; 1.
DR SUPFAM; SSF69721; SSF69721; 1.
DR TIGRFAMs; TIGR03342; dsrC_tusE_dsvC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transferase; tRNA processing.
FT CHAIN 1..109
FT /note="Sulfurtransferase TusE"
FT /id="PRO_0000234614"
FT ACT_SITE 108
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 109 AA; 12274 MW; CAF41EAFC0394D17 CRC64;
MLIFEGKEIS TDSEGYLKET TQWSEALAVA IAANEGIELS AEHWEVVRFV REFYLEFNTS
PAIRMLVKAM ANKFGEEKGN SRYLHRLFPK GPAKQATKIA GLPKPVKCI