TUSE_SHISS
ID TUSE_SHISS Reviewed; 109 AA.
AC Q3Z3F2;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 2.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Sulfurtransferase TusE;
DE EC=2.8.1.-;
DE AltName: Full=tRNA 2-thiouridine synthesizing protein E;
GN Name=tusE; OrderedLocusNames=SSON_0974;
OS Shigella sonnei (strain Ss046).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300269;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ss046;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Part of a sulfur-relay system required for 2-thiolation of 5-
CC methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
CC Could accept sulfur from TusD (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the TusBCD complex. Interacts with MnmA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DsrC/TusE family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAZ87710.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000038; AAZ87710.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; Q3Z3F2; -.
DR SMR; Q3Z3F2; -.
DR EnsemblBacteria; AAZ87710; AAZ87710; SSON_0974.
DR KEGG; ssn:SSON_0974; -.
DR HOGENOM; CLU_153199_0_0_6; -.
DR Proteomes; UP000002529; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.370; -; 1.
DR Gene3D; 3.30.1420.10; -; 1.
DR InterPro; IPR042072; DsrC-like_C.
DR InterPro; IPR025526; DsrC-like_dom_sf.
DR InterPro; IPR043163; DsrC-like_N.
DR InterPro; IPR007453; DsrC/TusE.
DR PANTHER; PTHR37010; PTHR37010; 1.
DR Pfam; PF04358; DsrC; 1.
DR PIRSF; PIRSF006223; DsrC_TusE; 1.
DR SUPFAM; SSF69721; SSF69721; 1.
DR TIGRFAMs; TIGR03342; dsrC_tusE_dsvC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transferase; tRNA processing.
FT CHAIN 1..109
FT /note="Sulfurtransferase TusE"
FT /id="PRO_0000234620"
FT ACT_SITE 108
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 109 AA; 12410 MW; FDB0CFF89114EBE7 CRC64;
MLIFEGKEIE TDTEGYLKES SQWSEPLAVV IAENEGISLS PEHWEVVRFV RDFYLEFNTS
PAIRMLVKAM ANKFGEEKGN SRYLYRLFPK GPAKQATKIA GLPKPVKCI