TUSE_SODGM
ID TUSE_SODGM Reviewed; 108 AA.
AC Q2NU63;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Sulfurtransferase TusE;
DE EC=2.8.1.-;
DE AltName: Full=tRNA 2-thiouridine synthesizing protein E;
GN Name=tusE; OrderedLocusNames=SG1037;
OS Sodalis glossinidius (strain morsitans).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=343509;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=morsitans;
RX PubMed=16365377; DOI=10.1101/gr.4106106;
RA Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA Aksoy S.;
RT "Massive genome erosion and functional adaptations provide insights into
RT the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL Genome Res. 16:149-156(2006).
CC -!- FUNCTION: Part of a sulfur-relay system required for 2-thiolation of 5-
CC methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
CC Could accept sulfur from TusD (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the TusBCD complex. Interacts with MnmA (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DsrC/TusE family. {ECO:0000305}.
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DR EMBL; AP008232; BAE74312.1; -; Genomic_DNA.
DR RefSeq; WP_011410897.1; NZ_LN854557.1.
DR AlphaFoldDB; Q2NU63; -.
DR SMR; Q2NU63; -.
DR STRING; 343509.SG1037; -.
DR PRIDE; Q2NU63; -.
DR EnsemblBacteria; BAE74312; BAE74312; SG1037.
DR KEGG; sgl:SG1037; -.
DR eggNOG; COG2920; Bacteria.
DR HOGENOM; CLU_153199_1_0_6; -.
DR OMA; EYNTSPA; -.
DR OrthoDB; 1840461at2; -.
DR Proteomes; UP000001932; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.370; -; 1.
DR Gene3D; 3.30.1420.10; -; 1.
DR InterPro; IPR042072; DsrC-like_C.
DR InterPro; IPR025526; DsrC-like_dom_sf.
DR InterPro; IPR043163; DsrC-like_N.
DR InterPro; IPR007453; DsrC/TusE.
DR PANTHER; PTHR37010; PTHR37010; 1.
DR Pfam; PF04358; DsrC; 1.
DR PIRSF; PIRSF006223; DsrC_TusE; 1.
DR SUPFAM; SSF69721; SSF69721; 1.
DR TIGRFAMs; TIGR03342; dsrC_tusE_dsvC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Transferase; tRNA processing.
FT CHAIN 1..108
FT /note="Sulfurtransferase TusE"
FT /id="PRO_0000234621"
FT ACT_SITE 107
FT /note="Cysteine persulfide intermediate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 108 AA; 12161 MW; FBBE9619AF62136F CRC64;
MEFNGTEIST DAQGYLTHLQ DWSEALAGEI ARREGITLSE AHWQVIHFVR AFYLQYNTSP
AVRMLVKAMA QAYGEEKGNS RYLFRLFPEG PAKQATKIAG LPKPVKCL