ID   C561_YERPE              Reviewed;         176 AA.
AC   Q9X6B2; Q0WBX1;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Probable cytochrome b561;
DE            Short=Cytochrome b-561;
GN   Name=cybB; Synonyms=cybB1; OrderedLocusNames=YPO3321, y0868, YP_0365;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KIM;
RX   PubMed=10322012; DOI=10.1128/jb.181.10.3114-3122.1999;
RA   Garcia E., Nedialkov Y.A., Elliott J., Motin V.L., Brubaker R.R.;
RT   "Molecular characterization of KatY (antigen 5), a thermoregulated
RT   chromosomally encoded catalase-peroxidase of Yersinia pestis.";
RL   J. Bacteriol. 181:3114-3122(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- COFACTOR:
CC       Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000250};
CC       Note=Binds 2 heme B (iron-protoporphyrin IX) groups per molecule.
CC       {ECO:0000250};
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cytochrome b561 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM84453.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAS60638.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF135170; AAD37315.1; -; Genomic_DNA.
DR   EMBL; AL590842; CAL21912.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM84453.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE017042; AAS60638.1; ALT_INIT; Genomic_DNA.
DR   PIR; AE0403; AE0403.
DR   RefSeq; WP_002215100.1; NZ_WUCM01000060.1.
DR   RefSeq; YP_002348217.1; NC_003143.1.
DR   AlphaFoldDB; Q9X6B2; -.
DR   SMR; Q9X6B2; -.
DR   STRING; 214092.YPO3321; -.
DR   PaxDb; Q9X6B2; -.
DR   PRIDE; Q9X6B2; -.
DR   EnsemblBacteria; AAM84453; AAM84453; y0868.
DR   EnsemblBacteria; AAS60638; AAS60638; YP_0365.
DR   GeneID; 57975388; -.
DR   KEGG; ype:YPO3321; -.
DR   KEGG; ypk:y0868; -.
DR   KEGG; ypm:YP_0365; -.
DR   PATRIC; fig|1028802.3.peg.1310; -.
DR   eggNOG; COG3038; Bacteria.
DR   HOGENOM; CLU_095321_3_0_6; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:InterPro.
DR   InterPro; IPR011577; Cyt_b561_bac/Ni-Hgenase.
DR   InterPro; IPR016174; Di-haem_cyt_TM.
DR   Pfam; PF01292; Ni_hydr_CYTB; 1.
DR   SUPFAM; SSF81342; SSF81342; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Electron transport; Heme; Iron;
KW   Membrane; Metal-binding; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..176
FT                   /note="Probable cytochrome b561"
FT                   /id="PRO_0000199973"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   BINDING         13
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255"
FT   BINDING         45
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255"
FT   BINDING         151
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255"
FT   BINDING         158
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   176 AA;  20037 MW;  4F59A28DC9F28C27 CRC64;
     MHKKYSCLQI GIHWLVLLLV IIAWSSIELR GFAPRSYQPW MKMIHFSCGI AILVLMMTRI
     LIQLRYPTPP IVPKPSPMIV GLAHVGHWVI YLLFIALPII GIAILYCRGS SWIAFGLIMP
     HAEQANFDLA DTLKAYHLLL ANMSYFVIGL HALAALLHHY VLKDNTLLRM MPKKRG