ID   TUS_ENT38               Reviewed;         309 AA.
AC   A4W9Y2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=DNA replication terminus site-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
DE            Short=Ter-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
GN   Name=tus {ECO:0000255|HAMAP-Rule:MF_00483}; OrderedLocusNames=Ent638_1833;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Trans-acting protein required for termination of DNA
CC       replication. Binds to DNA replication terminator sequences (terA to
CC       terF) to prevent the passage of replication forks. The termination
CC       efficiency will be affected by the affinity of this protein for the
CC       terminator sequence. {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SIMILARITY: Belongs to the Tus family. {ECO:0000255|HAMAP-
CC       Rule:MF_00483}.
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DR   EMBL; CP000653; ABP60512.1; -; Genomic_DNA.
DR   RefSeq; WP_012017227.1; NC_009436.1.
DR   AlphaFoldDB; A4W9Y2; -.
DR   SMR; A4W9Y2; -.
DR   STRING; 399742.Ent638_1833; -.
DR   EnsemblBacteria; ABP60512; ABP60512; Ent638_1833.
DR   KEGG; ent:Ent638_1833; -.
DR   eggNOG; ENOG502Z895; Bacteria.
DR   HOGENOM; CLU_078181_0_0_6; -.
DR   OMA; QVQYACP; -.
DR   OrthoDB; 815244at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006274; P:DNA replication termination; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.14.10; -; 1.
DR   HAMAP; MF_00483; Rep_term_Tus; 1.
DR   InterPro; IPR008865; DNA_replication_term_site-bd.
DR   InterPro; IPR036381; Tus_dom1.
DR   InterPro; IPR036384; Tus_sf.
DR   Pfam; PF05472; Ter; 1.
DR   SUPFAM; SSF56596; SSF56596; 1.
DR   TIGRFAMs; TIGR02648; rep_term_tus; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA replication; DNA-binding.
FT   CHAIN           1..309
FT                   /note="DNA replication terminus site-binding protein"
FT                   /id="PRO_1000060427"
SQ   SEQUENCE   309 AA;  35464 MW;  13697B0A606D3C96 CRC64;
     MATYDLIERL NSTFRQIELE LVTLTERLKG CRLLAARVFT LPDVAKGAEH DELNTIEVEQ
     HIGQEAVALT LAHYRHLFIH QQSEKRSSKA AVRLPGVICL QCDGALREEI ESQIAHINTL
     KMAFEKIITE ESGLPPAARF EWVHRQLPGL ITLNAYRSLT VLRQPATLRF GWANKHIIKN
     FTRDDVLSLL EKSLKSPRTV TPWSREQWIE RLEEEYDNIA ALPAETRLKI KRPVKVQPIA
     RVWYAGQQKQ VQYACPTPMI ALFDAEQGAM VPDIGELLNY DADNIQHRYK PQAQPLRLII
     PRLHLYVAE