ID   TUS_SALDC               Reviewed;         309 AA.
AC   B5FID6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=DNA replication terminus site-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
DE            Short=Ter-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
GN   Name=tus {ECO:0000255|HAMAP-Rule:MF_00483}; OrderedLocusNames=SeD_A1873;
OS   Salmonella dublin (strain CT_02021853).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=439851;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT_02021853;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Trans-acting protein required for termination of DNA
CC       replication. Binds to DNA replication terminator sequences (terA to
CC       terF) to prevent the passage of replication forks. The termination
CC       efficiency will be affected by the affinity of this protein for the
CC       terminator sequence. {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SIMILARITY: Belongs to the Tus family. {ECO:0000255|HAMAP-
CC       Rule:MF_00483}.
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DR   EMBL; CP001144; ACH77911.1; -; Genomic_DNA.
DR   RefSeq; WP_000092497.1; NC_011205.1.
DR   AlphaFoldDB; B5FID6; -.
DR   SMR; B5FID6; -.
DR   KEGG; sed:SeD_A1873; -.
DR   HOGENOM; CLU_078181_0_0_6; -.
DR   OMA; QVQYACP; -.
DR   Proteomes; UP000008322; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006274; P:DNA replication termination; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.14.10; -; 1.
DR   HAMAP; MF_00483; Rep_term_Tus; 1.
DR   InterPro; IPR008865; DNA_replication_term_site-bd.
DR   InterPro; IPR036381; Tus_dom1.
DR   InterPro; IPR036384; Tus_sf.
DR   Pfam; PF05472; Ter; 1.
DR   SUPFAM; SSF56596; SSF56596; 1.
DR   TIGRFAMs; TIGR02648; rep_term_tus; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA replication; DNA-binding.
FT   CHAIN           1..309
FT                   /note="DNA replication terminus site-binding protein"
FT                   /id="PRO_1000126043"
SQ   SEQUENCE   309 AA;  35487 MW;  9BB37AD7A23DD8B1 CRC64;
     MSRYDLVERL NGTFRQIEQH LAALTDNLQQ HSLLIARVFS LPQVTKEAEH APLDTIEVTQ
     HLGKEAETLA LRHYRHLFIQ QQSENRSSKA AVRLPGVLCY QVDNATQLDL ENQVQRINQL
     KTTFEQMVTV ESGLPSAARF EWVHRHLPGL ITLNAYRTLT LINNPATIRF GWANKHIIKN
     LSRDEVLSQL KKSLASPRSV PPWTREQWQF KLEREYQDIA ALPQQARLKI KRPVKVQPIA
     RIWYKGQQKQ VQHACPTPII ALINTDNGAG VPDIGGLENY DADNIQHRFK PQAQPLRLII
     PRLHLYVAD