ID   TUS_YERPS               Reviewed;         311 AA.
AC   Q66AE3;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=DNA replication terminus site-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
DE            Short=Ter-binding protein {ECO:0000255|HAMAP-Rule:MF_00483};
GN   Name=tus {ECO:0000255|HAMAP-Rule:MF_00483}; OrderedLocusNames=YPTB2187;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Trans-acting protein required for termination of DNA
CC       replication. Binds to DNA replication terminator sequences (terA to
CC       terF) to prevent the passage of replication forks. The termination
CC       efficiency will be affected by the affinity of this protein for the
CC       terminator sequence. {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00483}.
CC   -!- SIMILARITY: Belongs to the Tus family. {ECO:0000255|HAMAP-
CC       Rule:MF_00483}.
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DR   EMBL; BX936398; CAH21425.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q66AE3; -.
DR   SMR; Q66AE3; -.
DR   EnsemblBacteria; CAH21425; CAH21425; YPTB2187.
DR   KEGG; ypo:BZ17_274; -.
DR   KEGG; yps:YPTB2187; -.
DR   PATRIC; fig|273123.14.peg.290; -.
DR   OMA; QVQYACP; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006274; P:DNA replication termination; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.14.10; -; 1.
DR   HAMAP; MF_00483; Rep_term_Tus; 1.
DR   InterPro; IPR008865; DNA_replication_term_site-bd.
DR   InterPro; IPR036381; Tus_dom1.
DR   InterPro; IPR036384; Tus_sf.
DR   Pfam; PF05472; Ter; 1.
DR   SUPFAM; SSF56596; SSF56596; 1.
DR   TIGRFAMs; TIGR02648; rep_term_tus; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA replication; DNA-binding.
FT   CHAIN           1..311
FT                   /note="DNA replication terminus site-binding protein"
FT                   /id="PRO_0000049425"
SQ   SEQUENCE   311 AA;  36201 MW;  4FA87BC32E08BCF7 CRC64;
     MNKYDLIERM NTRFAELEVT LHQLHQQLDD LPLIAARVFS LPEIEKGTEH QPIEQITVNI
     TEGEHAKRLG LQHFQRLFLH HQGQHVSSKA ALRLPGVLCF SVTDKELIEC QDIIKKTNQL
     KAELEHIITV ESGLPSEQRF EFVHTHLHGL ITLNTYRTIT PLINPSSVRF GWANKHIIKN
     VTREDILLQL EKSLNAGRAV PPFTREQWRE LISLEINDVQ RLPEKTRLKI KRPVKVQPIA
     RVWYQEQQKQ VQHPCPMPLI AFCQRQSGAE LPKLGELTDY DVKHIKHKYK PDAKPLRLLV
     PRLHLYVELE P