TVA1_MOUSE
ID TVA1_MOUSE Reviewed; 130 AA.
AC P01738;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=T-cell receptor alpha chain V region PHDS58;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BALB.B;
RX PubMed=6208487; DOI=10.1038/312036a0;
RA Saito H., Kranz D.M., Takagaki Y., Hayday A.C., Eisen H.N., Tonegawa S.;
RT "A third rearranged and expressed gene in a clone of cytotoxic T
RT lymphocytes.";
RL Nature 312:36-40(1984).
CC -!- MISCELLANEOUS: This clone was isolated from a cytotoxic T lymphocyte.
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DR PIR; A02012; RWMS58.
DR PDB; 1G6R; X-ray; 2.80 A; A/C=21-130.
DR PDB; 1I9E; X-ray; 2.50 A; A=21-130.
DR PDB; 1MWA; X-ray; 2.40 A; A/C=21-130.
DR PDB; 1TCR; X-ray; 2.50 A; A=21-130.
DR PDB; 2CKB; X-ray; 3.00 A; A/C=21-130.
DR PDB; 2ICW; X-ray; 2.41 A; I/K=21-130.
DR PDB; 2OI9; X-ray; 2.35 A; B=21-130.
DR PDB; 3E2H; X-ray; 3.80 A; B=22-130.
DR PDB; 3E3Q; X-ray; 2.95 A; C/D/I/M/R/V/Z/d=22-130.
DR PDB; 4MVB; X-ray; 3.09 A; A=20-129.
DR PDB; 4MXQ; X-ray; 2.60 A; C=20-113.
DR PDB; 4N0C; X-ray; 2.90 A; C/G=20-129.
DR PDB; 4N5E; X-ray; 3.06 A; C=20-113.
DR PDB; 4NHU; X-ray; 2.90 A; A/C=21-130.
DR PDBsum; 1G6R; -.
DR PDBsum; 1I9E; -.
DR PDBsum; 1MWA; -.
DR PDBsum; 1TCR; -.
DR PDBsum; 2CKB; -.
DR PDBsum; 2ICW; -.
DR PDBsum; 2OI9; -.
DR PDBsum; 3E2H; -.
DR PDBsum; 3E3Q; -.
DR PDBsum; 4MVB; -.
DR PDBsum; 4MXQ; -.
DR PDBsum; 4N0C; -.
DR PDBsum; 4N5E; -.
DR PDBsum; 4NHU; -.
DR AlphaFoldDB; P01738; -.
DR SMR; P01738; -.
DR MINT; P01738; -.
DR GlyGen; P01738; 1 site.
DR PRIDE; P01738; -.
DR EvolutionaryTrace; P01738; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01738; protein.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Glycoprotein; Immunity;
KW Immunoglobulin domain; Receptor; Reference proteome; Signal;
KW T cell receptor.
FT SIGNAL 1..20
FT CHAIN 21..130
FT /note="T-cell receptor alpha chain V region PHDS58"
FT /id="PRO_0000033591"
FT REGION 21..114
FT /note="V segment"
FT REGION 115..130
FT /note="J segment"
FT CARBOHYD 90
FT /note="N-linked (GlcNAc...) asparagine"
FT NON_TER 130
FT STRAND 22..24
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 28..33
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 38..40
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 43..45
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 52..57
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 59..61
FT /evidence="ECO:0007829|PDB:2CKB"
FT STRAND 64..69
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 74..77
FT /evidence="ECO:0007829|PDB:2OI9"
FT HELIX 79..81
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 82..87
FT /evidence="ECO:0007829|PDB:2OI9"
FT TURN 88..91
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 92..99
FT /evidence="ECO:0007829|PDB:2OI9"
FT HELIX 102..104
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 106..113
FT /evidence="ECO:0007829|PDB:2OI9"
FT HELIX 115..117
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 119..121
FT /evidence="ECO:0007829|PDB:2OI9"
FT STRAND 125..130
FT /evidence="ECO:0007829|PDB:2OI9"
SQ SEQUENCE 130 AA; 14320 MW; 19E638A8EEBFA635 CRC64;
MLLALLPVLG IHFVLRDAQA QSVTQPDARV TVSEGASLQL RCKYSYSATP YLFWYVQYPR
QGLQLLLKYY SGDPVVQGVN GFEAEFSKSN SSFHLRKASV HWSDSAVYFC AVSGFASALT
FGSGTKVIVL
