TVA3_MOUSE
ID TVA3_MOUSE Reviewed; 132 AA.
AC P06323;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=T-cell receptor alpha chain V region CTL-F3;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=3490968; DOI=10.1002/j.1460-2075.1986.tb04478.x;
RA Chou H.S., Behlke M.A., Godambe S.A., Russell J.H., Brooks C.G., Loh D.Y.;
RT "T cell receptor genes in an alloreactive CTL clone: implications for
RT rearrangement and germline diversity of variable gene segments.";
RL EMBO J. 5:2149-2155(1986).
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DR PIR; A02014; RWMSA3.
DR PIR; A24891; A24891.
DR PDB; 1AC6; X-ray; 2.30 A; A/B=23-129.
DR PDBsum; 1AC6; -.
DR AlphaFoldDB; P06323; -.
DR SMR; P06323; -.
DR GlyGen; P06323; 1 site.
DR PRIDE; P06323; -.
DR EvolutionaryTrace; P06323; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P06323; protein.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Disulfide bond; Glycoprotein; Immunity;
KW Immunoglobulin domain; Receptor; Reference proteome; Signal;
KW T cell receptor.
FT SIGNAL 1..22
FT CHAIN 23..132
FT /note="T-cell receptor alpha chain V region CTL-F3"
FT /id="PRO_0000033596"
FT REGION 23..114
FT /note="V segment"
FT REGION 115..132
FT /note="J segment"
FT CARBOHYD 43
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 44..111
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 132
SQ SEQUENCE 132 AA; 14747 MW; 4E7DCB0D7FEDAA67 CRC64;
MNMRPDTCSV LVLLLMLRRN NGDSVTQTEG LVTLTEGLPV MLNCTYQSTY SPFLFWYVQH
LNEAPKLLFK SFTDNKRPEH QGFHATLHKS SSSFHLQKSS AQLSDSALYY CALSNAGAKL
TFGGGTRLTV RP