TVB4_MOUSE
ID TVB4_MOUSE Reviewed; 136 AA.
AC P04212;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-1987, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=T-cell receptor beta chain V region LB2;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=6092964; DOI=10.1038/312040a0;
RA Patten P., Yokota T., Rothbard J., Chien Y., Arai K., Davis M.M.;
RT "Structure, expression and divergence of T-cell receptor beta-chain
RT variable regions.";
RL Nature 312:40-46(1984).
CC -!- MISCELLANEOUS: This sequence was derived from a T-helper clone.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X01643; CAA25800.1; -; mRNA.
DR PIR; A02007; RWMSLB.
DR AlphaFoldDB; P04212; -.
DR SMR; P04212; -.
DR IntAct; P04212; 1.
DR PRIDE; P04212; -.
DR UCSC; uc009boj.1; mouse.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P04212; protein.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Adaptive immunity; Disulfide bond; Immunity; Immunoglobulin domain;
KW Receptor; Reference proteome; Signal; T cell receptor.
FT SIGNAL 1..21
FT CHAIN 22..136
FT /note="T-cell receptor beta chain V region LB2"
FT /id="PRO_0000033602"
FT REGION 22..116
FT /note="V segment"
FT REGION 117..120
FT /note="D segment"
FT REGION 121..136
FT /note="J segment"
FT DISULFID 45..113
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 136
SQ SEQUENCE 136 AA; 15369 MW; F74D0C0414088D02 CRC64;
MNKWVFCWVT LCLLTVETTH GDGGIITQTP KFLIGQEGQK LTLKCQQNFN HDTMYWYRQD
SGKGLRLIYY SITENDLQKG DLSEGYDASR EKKSSFSLTV TSAQKNEMTV FLCASSIRLA
SAETLYFGSG TRLTVL