TVB5_MOUSE
ID TVB5_MOUSE Reviewed; 122 AA.
AC P04213;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-1987, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=T-cell receptor beta chain V region C5;
DE Flags: Precursor; Fragment;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=6092964; DOI=10.1038/312040a0;
RA Patten P., Yokota T., Rothbard J., Chien Y., Arai K., Davis M.M.;
RT "Structure, expression and divergence of T-cell receptor beta-chain
RT variable regions.";
RL Nature 312:40-46(1984).
CC -!- MISCELLANEOUS: This sequence was derived from a T-helper clone.
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DR PIR; A02008; RWMSC5.
DR PDB; 1D9K; X-ray; 3.20 A; B/F=11-122.
DR PDB; 1LP9; X-ray; 2.00 A; F/M=8-122.
DR PDB; 1U3H; X-ray; 2.42 A; B/F=11-122.
DR PDB; 2APB; X-ray; 1.80 A; A=9-122.
DR PDB; 2APF; X-ray; 1.80 A; A=9-122.
DR PDB; 2APT; X-ray; 2.00 A; A/B=9-106.
DR PDB; 2APV; X-ray; 1.90 A; A=9-106.
DR PDB; 2APW; X-ray; 2.00 A; A=9-106.
DR PDB; 2APX; X-ray; 1.80 A; A=9-106.
DR PDB; 2AQ1; X-ray; 2.10 A; A/C/E/G=9-122.
DR PDB; 2AQ2; X-ray; 1.80 A; A=9-122.
DR PDB; 2AQ3; X-ray; 2.30 A; A/C/E/G=9-122.
DR PDB; 2J8U; X-ray; 2.88 A; F/M=8-122.
DR PDB; 2UWE; X-ray; 2.40 A; F/M=8-122.
DR PDB; 4NHU; X-ray; 2.90 A; B/D=9-101.
DR PDB; 5M00; X-ray; 1.95 A; H=11-102.
DR PDB; 5M01; X-ray; 1.95 A; H=11-102.
DR PDB; 5M02; X-ray; 1.75 A; H=11-102.
DR PDB; 5WLG; X-ray; 2.10 A; E/J=9-102.
DR PDB; 6G9Q; X-ray; 1.89 A; H=11-122.
DR PDBsum; 1D9K; -.
DR PDBsum; 1LP9; -.
DR PDBsum; 1U3H; -.
DR PDBsum; 2APB; -.
DR PDBsum; 2APF; -.
DR PDBsum; 2APT; -.
DR PDBsum; 2APV; -.
DR PDBsum; 2APW; -.
DR PDBsum; 2APX; -.
DR PDBsum; 2AQ1; -.
DR PDBsum; 2AQ2; -.
DR PDBsum; 2AQ3; -.
DR PDBsum; 2J8U; -.
DR PDBsum; 2UWE; -.
DR PDBsum; 4NHU; -.
DR PDBsum; 5M00; -.
DR PDBsum; 5M01; -.
DR PDBsum; 5M02; -.
DR PDBsum; 5WLG; -.
DR PDBsum; 6G9Q; -.
DR AlphaFoldDB; P04213; -.
DR SMR; P04213; -.
DR IntAct; P04213; 1.
DR iPTMnet; P04213; -.
DR PhosphoSitePlus; P04213; -.
DR EPD; P04213; -.
DR PRIDE; P04213; -.
DR UCSC; uc009boc.2; mouse.
DR EvolutionaryTrace; P04213; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P04213; protein.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Disulfide bond; Immunity;
KW Immunoglobulin domain; Receptor; Reference proteome; Signal;
KW T cell receptor.
FT SIGNAL <1..7
FT CHAIN 8..122
FT /note="T-cell receptor beta chain V region C5"
FT /id="PRO_0000033603"
FT REGION 8..103
FT /note="V segment"
FT REGION 104..108
FT /note="D segment"
FT REGION 109..122
FT /note="J segment"
FT DISULFID 31..99
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 1
FT NON_TER 122
FT STRAND 12..15
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 17..22
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 27..33
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 38..46
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 49..59
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 62..65
FT /evidence="ECO:0007829|PDB:5M00"
FT STRAND 73..75
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 78..88
FT /evidence="ECO:0007829|PDB:5M02"
FT HELIX 91..93
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 95..102
FT /evidence="ECO:0007829|PDB:5M02"
FT STRAND 104..108
FT /evidence="ECO:0007829|PDB:1U3H"
FT STRAND 111..113
FT /evidence="ECO:0007829|PDB:1U3H"
FT STRAND 117..121
FT /evidence="ECO:0007829|PDB:2AQ2"
SQ SEQUENCE 122 AA; 13349 MW; D657DCC9B261C64C CRC64;
ILLCAKHMEA AVTQSPRSKV AVTGGKVTLS CHQTNNHDYM YWYRQDTGHG LRLIHYSYVA
DSTEKGDIPD GYKASRPSQE NFSLILELAS LSQTAVYFCA SSGTGGALDT QYFGPGTRLL
VL
