TVB6_MOUSE
ID TVB6_MOUSE Reviewed; 136 AA.
AC P04214;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-1987, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=T-cell receptor beta chain V region E1;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=6092964; DOI=10.1038/312040a0;
RA Patten P., Yokota T., Rothbard J., Chien Y., Arai K., Davis M.M.;
RT "Structure, expression and divergence of T-cell receptor beta-chain
RT variable regions.";
RL Nature 312:40-46(1984).
CC -!- MISCELLANEOUS: This sequence was derived from a T-helper clone.
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DR EMBL; X01642; CAA25799.1; -; mRNA.
DR PIR; A02009; RWMSE1.
DR PDB; 1FO0; X-ray; 2.50 A; B=22-131.
DR PDB; 1KB5; X-ray; 2.50 A; B=22-116.
DR PDB; 1KJ2; X-ray; 2.71 A; B/E=22-136.
DR PDB; 1NAM; X-ray; 2.70 A; B=22-135.
DR PDB; 2OL3; X-ray; 2.90 A; B=22-136.
DR PDBsum; 1FO0; -.
DR PDBsum; 1KB5; -.
DR PDBsum; 1KJ2; -.
DR PDBsum; 1NAM; -.
DR PDBsum; 2OL3; -.
DR AlphaFoldDB; P04214; -.
DR SMR; P04214; -.
DR IntAct; P04214; 1.
DR PRIDE; P04214; -.
DR ABCD; P04214; 1 sequenced antibody.
DR UCSC; uc009bni.2; mouse.
DR EvolutionaryTrace; P04214; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P04214; protein.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0042605; F:peptide antigen binding; IBA:GO_Central.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Adaptive immunity; Disulfide bond; Immunity;
KW Immunoglobulin domain; Receptor; Reference proteome; Signal;
KW T cell receptor.
FT SIGNAL 1..20
FT CHAIN 21..136
FT /note="T-cell receptor beta chain V region E1"
FT /id="PRO_0000033604"
FT REGION 21..116
FT /note="V segment"
FT REGION 117..120
FT /note="D segment"
FT REGION 121..136
FT /note="J segment"
FT DISULFID 44..112
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT NON_TER 136
FT STRAND 24..28
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 30..33
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 36..38
FT /evidence="ECO:0007829|PDB:1KB5"
FT STRAND 40..47
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 53..59
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 65..70
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 77..82
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 85..93
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 96..103
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 108..115
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 118..122
FT /evidence="ECO:0007829|PDB:1FO0"
FT STRAND 131..133
FT /evidence="ECO:0007829|PDB:1FO0"
SQ SEQUENCE 136 AA; 15538 MW; 2B93C4912E19B705 CRC64;
MWQFCILCLC VLMASVATDP TVTLLEQNPR WRLVPRGQAV NLRCILKNSQ YPWMSWYQQD
LQKQLQWLFT LRSPRDKEVK SLPGADYLAT RVTDTELRLQ VANMSQGRTL YCTCSATGGL
NTGQLYFGEG SKLTVL
