TVB8_MOUSE
ID TVB8_MOUSE Reviewed; 130 AA.
AC P06321;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=T-cell receptor beta chain V region A20.2.25;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=3906657; DOI=10.1073/pnas.82.23.8163;
RA Morinaga T., Fotedar A., Singh B., Wegmann T.G., Tamaoki T.;
RT "Isolation of cDNA clones encoding a T-cell receptor beta-chain from a beef
RT insulin-specific hybridoma.";
RL Proc. Natl. Acad. Sci. U.S.A. 82:8163-8167(1985).
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DR PIR; A02005; RWMS20.
DR AlphaFoldDB; P06321; -.
DR SMR; P06321; -.
DR GlyGen; P06321; 2 sites.
DR PRIDE; P06321; -.
DR UCSC; uc009bnv.2; mouse.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P06321; protein.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Adaptive immunity; Glycoprotein; Immunity; Immunoglobulin domain; Receptor;
KW Reference proteome; Signal; T cell receptor.
FT SIGNAL 1..21
FT /evidence="ECO:0000250"
FT CHAIN 22..>130
FT /note="T-cell receptor beta chain V region A20.2.25"
FT /id="PRO_0000033606"
FT REGION 22..112
FT /note="V segment"
FT REGION 113..115
FT /note="D segment"
FT REGION 116..130
FT /note="J segment"
FT CARBOHYD 36
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 75
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT NON_TER 130
SQ SEQUENCE 130 AA; 14732 MW; 6721EC70DC64BEDB CRC64;
MSCRLLLYVS LCLVETALMN TKITQSPRYL ILGRANKSLE CEQHLGHNAM YWYKQSAEKP
PELMFLYNLK QLIRNETVPS RFIPECPDSS KLLLHISAVD PEDSAVYFCA SSHGENTEVF
FGKGTTLTVV