TVC1_MOUSE
ID TVC1_MOUSE Reviewed; 135 AA.
AC P01740;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-1986, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=T-cell receptor gamma chain V region V108A;
DE Flags: Precursor;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=3917858; DOI=10.1016/0092-8674(85)90140-0;
RA Hayday A.C., Saito H., Gillies S.D., Kranz D.M., Tanigawa G., Eisen H.N.,
RA Tonegawa S.;
RT "Structure, organization, and somatic rearrangement of T cell gamma
RT genes.";
RL Cell 40:259-269(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE (CLONE PHDS4/PHDS203).
RC STRAIN=BALB.B;
RX PubMed=6330561; DOI=10.1038/309757a0;
RA Saito H., Kranz D.M., Takagaki Y., Hayday A.C., Eisen H.N., Tonegawa S.;
RT "Complete primary structure of a heterodimeric T-cell receptor deduced from
RT cDNA sequences.";
RL Nature 309:757-762(1984).
CC -!- MISCELLANEOUS: This mRNA was isolated from a cytotoxic T-lymphocyte.
CC The gene corresponding to this mRNA is rearranged specifically in T-
CC cells and its organization is similar to an Ig gene, with V (or V+D),
CC J, and C regions.
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DR PIR; A90859; RWMSV1.
DR AlphaFoldDB; P01740; -.
DR SMR; P01740; -.
DR PRIDE; P01740; -.
DR UCSC; uc007pow.1; mouse.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P01740; protein.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0042101; C:T cell receptor complex; IEA:UniProtKB-KW.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; SSF48726; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Adaptive immunity; Immunity; Immunoglobulin domain; Receptor;
KW Reference proteome; Signal; T cell receptor.
FT SIGNAL 1..18
FT CHAIN 19..135
FT /note="T-cell receptor gamma chain V region V108A"
FT /id="PRO_0000033607"
FT REGION 19..116
FT /note="V segment"
FT REGION 117..135
FT /note="J segment"
FT NON_TER 135
SQ SEQUENCE 135 AA; 15930 MW; 402145C95E924D7D CRC64;
MLLLRWFTSC CLWVFGLGQL EQTELSVTRE TDENVQISCI VYLPYFSNTA IHWYRQKTNQ
QFEYLIYVAT NYNQRPLGGK HKKIEASKDF KSSTSTLEIN YLKKEDEATY YCAVWMRWSS
GFHKVFAEGT KLIVI