ID   TVID_SALTI              Reviewed;         831 AA.
AC   Q04974;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   05-DEC-2001, sequence version 2.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Vi polysaccharide biosynthesis protein TviD;
GN   Name=tviD; OrderedLocusNames=STY4659, t4350;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GIFU 10007;
RX   PubMed=8331073; DOI=10.1128/jb.175.14.4456-4465.1993;
RA   Hashimoto Y., Li N., Yokoyama H., Ezaki T.;
RT   "Complete nucleotide sequence and molecular characterization of ViaB region
RT   encoding Vi antigen in Salmonella typhi.";
RL   J. Bacteriol. 175:4456-4465(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 101-831.
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=8248629; DOI=10.1016/0923-2508(93)90193-6;
RA   Waxin H., Virlogeux I., Kolyva S., Popoff M.Y.;
RT   "Identification of six open reading frames in the Salmonella enterica
RT   subsp. enterica ser. Typhi viaB locus involved in Vi antigen production.";
RL   Res. Microbiol. 144:363-371(1993).
CC   -!- FUNCTION: May be required for maturation of the Vi polysaccharide.
CC   -!- PATHWAY: Glycan metabolism; Vi-antigen biosynthesis.
CC   -!- PATHWAY: Capsule biogenesis; capsule polysaccharide biosynthesis.
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DR   EMBL; D14156; BAA03194.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD06779.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71803.1; -; Genomic_DNA.
DR   EMBL; X67785; CAA47993.1; -; Genomic_DNA.
DR   PIR; D36892; D36892.
DR   RefSeq; NP_458738.1; NC_003198.1.
DR   RefSeq; WP_010989299.1; NZ_WSUR01000012.1.
DR   AlphaFoldDB; Q04974; -.
DR   STRING; 220341.16505429; -.
DR   EnsemblBacteria; AAO71803; AAO71803; t4350.
DR   KEGG; stt:t4350; -.
DR   KEGG; sty:STY4659; -.
DR   PATRIC; fig|220341.7.peg.4758; -.
DR   eggNOG; COG0457; Bacteria.
DR   HOGENOM; CLU_342776_0_0_6; -.
DR   OMA; RHINNIP; -.
DR   UniPathway; UPA00811; -.
DR   UniPathway; UPA00934; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0045227; P:capsule polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
FT   CHAIN           1..831
FT                   /note="Vi polysaccharide biosynthesis protein TviD"
FT                   /id="PRO_0000065699"
FT   CONFLICT        290
FT                   /note="R -> S (in Ref. 4; CAA47993)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        293
FT                   /note="T -> A (in Ref. 1; BAA03194)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   831 AA;  95438 MW;  C36561D0FCB76ACE CRC64;
     MNLMKSSGMF TLTAIGSCRI VSPVKRAQPY FNFQANFKRI YGFTHTSSEA LQQIRFILGL
     IDIPEKVRPF IFRPNVNYSN TDVHSRSDFY IIEISSQKKI MAYGFCLQIN YLTRHFYEFF
     SQTERACMYW SLATQGNRHK LLAYLKDDPC FAGMSEDDRA LLSNINVEQM DEHAIEQDMM
     EIVQLLGRDR VMFMTHVDAV TRAGTVILSR SRLIKNVDTI AARMDIPCVN PTNLMEKWGQ
     KRALEKNGDD LTHYTDMFGD AIVAAIFKGV INNTNHHLDE GRQEKQDQIR EITLSITKQL
     ADGDIIAASQ QLFAALRNQQ QDPVLIQLRS VIFSHLGYYE QAYQDISDVE KIIGTTDSTL
     RCRLRSLHGL ARWREALSTA EMMLSNEIED EEVLTVAAGS ADALQLFDKS YHYWKRVLLL
     NPETQSGWVN FLSSTQYFND GNAFSEAFHA GIQSQRLNDT FMETALSLAI KFSDELIFMH
     ALEQLLRHES EFALTVLSTI HDTGLVIRTA FCIKNMSYHQ ALRTSYKDKI HDVFEAWNNT
     ALSLHSVDDF VSLSTSLAYS YSAFMVYPHS RISRFNNEVK MAWRDKLREM YEREDYENIL
     AGAKIVWPLL KFDPVGTVYC ARTLVNLGAW KDACTLAHMT LIRNSNITSL QSIMLRSIRH
     INNIPFLIDL IANVMSITLS FQNASMNKLF EKECRNVATR ALKYVRQKKT EGRLDEALSV
     LISLKRIEPD VSRLMREYKQ IIRLFNESRK DGGSTITSYE HLDYAKKLLV FDSENAYALK
     YAALNAMHLR DYTQALQYWQ RLEKVNGPTE PVTRQISTCI TALQKNTSGK S