ID   TVP15_SCHPO             Reviewed;         132 AA.
AC   O14223;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Golgi apparatus membrane protein tvp15;
GN   Name=tvp15; ORFNames=SPAC6F12.04;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the TVP15 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB11088.1; -; Genomic_DNA.
DR   PIR; T11655; T11655.
DR   RefSeq; NP_593290.1; NM_001018720.2.
DR   AlphaFoldDB; O14223; -.
DR   SMR; O14223; -.
DR   BioGRID; 279183; 20.
DR   IntAct; O14223; 2.
DR   STRING; 4896.SPAC6F12.04.1; -.
DR   PaxDb; O14223; -.
DR   EnsemblFungi; SPAC6F12.04.1; SPAC6F12.04.1:pep; SPAC6F12.04.
DR   GeneID; 2542733; -.
DR   KEGG; spo:SPAC6F12.04; -.
DR   PomBase; SPAC6F12.04; tvp15.
DR   VEuPathDB; FungiDB:SPAC6F12.04; -.
DR   eggNOG; ENOG502S6ZT; Eukaryota.
DR   HOGENOM; CLU_120579_0_0_1; -.
DR   InParanoid; O14223; -.
DR   OMA; YVALEFI; -.
DR   PhylomeDB; O14223; -.
DR   PRO; PR:O14223; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0030137; C:COPI-coated vesicle; ISO:PomBase.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR013714; Golgi_TVP15.
DR   PANTHER; PTHR28128; PTHR28128; 1.
DR   Pfam; PF08507; COPI_assoc; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..132
FT                   /note="Golgi apparatus membrane protein tvp15"
FT                   /id="PRO_0000339145"
FT   TOPO_DOM        1..3
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        25
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..56
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        78..89
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        113..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   132 AA;  14518 MW;  E58A461BA9F3A0B0 CRC64;
     MDKTKMFSAI NLGVGGIFVL SGFIKLFSFS FVNALLALFI IVFGLGTIGL EKEIPPIAIK
     YGSFMFSFLG RGFFYAFMGT LLFSYSGFTS FLGFLVLLAG IAYCGANYVA GLQDYAPRSM
     RDNDWDDNVD EV