ID   TVP18_AJECN             Reviewed;         146 AA.
AC   A6QRX6;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Golgi apparatus membrane protein TVP18;
GN   Name=TVP18; ORFNames=HCAG_00132;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
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DR   EMBL; CH476655; EDN02268.1; -; Genomic_DNA.
DR   RefSeq; XP_001543086.1; XM_001543036.1.
DR   AlphaFoldDB; A6QRX6; -.
DR   STRING; 339724.A6QRX6; -.
DR   EnsemblFungi; EDN02268; EDN02268; HCAG_00132.
DR   GeneID; 5450196; -.
DR   KEGG; aje:HCAG_00132; -.
DR   VEuPathDB; FungiDB:HCAG_00132; -.
DR   HOGENOM; CLU_118698_0_0_1; -.
DR   OMA; ETNYMRA; -.
DR   OrthoDB; 1497869at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IEA:EnsemblFungi.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:EnsemblFungi.
DR   InterPro; IPR019365; TVP18/Ca-channel_flower.
DR   PANTHER; PTHR13314; PTHR13314; 1.
DR   Pfam; PF10233; Cg6151-P; 1.
DR   SMART; SM01077; Cg6151-P; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..146
FT                   /note="Golgi apparatus membrane protein TVP18"
FT                   /id="PRO_0000343008"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        11
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   146 AA;  15938 MW;  6B8C4B4DD51BA619 CRC64;
     MTIAEEFKSR NFSIYGQWTG VLCILLCFAL GIANIFSKVI AFSIVCLASS FVIIFVEVPL
     LLRICPTSST FDSFIRRFTT NYMRALMYVI LSVVQWLSLI VGPSSLLAAA VVLSVSAIFY
     ALAGITKQEF MGSKTLGGQG VAQMIV