TVP18_CANAL
ID TVP18_CANAL Reviewed; 173 AA.
AC Q5APC0; A0A1D8PEP3;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Golgi apparatus membrane protein TVP18;
GN Name=TVP18; OrderedLocusNames=CAALFM_C109800CA;
GN ORFNames=CaO19.12308, CaO19.4845;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
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DR EMBL; CP017623; AOW26612.1; -; Genomic_DNA.
DR RefSeq; XP_723531.1; XM_718438.2.
DR AlphaFoldDB; Q5APC0; -.
DR STRING; 237561.Q5APC0; -.
DR GeneID; 3634844; -.
DR KEGG; cal:CAALFM_C109800CA; -.
DR CGD; CAL0000196216; TVP18.
DR VEuPathDB; FungiDB:C1_09800C_A; -.
DR eggNOG; ENOG502S3AC; Eukaryota.
DR HOGENOM; CLU_118698_1_0_1; -.
DR InParanoid; Q5APC0; -.
DR OMA; ETNYMRA; -.
DR OrthoDB; 1497869at2759; -.
DR PRO; PR:Q5APC0; -.
DR Proteomes; UP000000559; Chromosome 1.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR InterPro; IPR019365; TVP18/Ca-channel_flower.
DR PANTHER; PTHR13314; PTHR13314; 1.
DR Pfam; PF10233; Cg6151-P; 1.
DR SMART; SM01077; Cg6151-P; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..173
FT /note="Golgi apparatus membrane protein TVP18"
FT /id="PRO_0000343015"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 23
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 173 AA; 18800 MW; 023292EF59D72528 CRC64;
MALADLALSN IWGGLSSDFK KKNFSLYGQW ISILTIFLCL ALGVANIFHL GPIIVFSIIC
IVQGLIVLFV EVPFLLKICP LTDTFVNFVR KFDGNLPRCG FYLLNAVIQY LSLTLQATSL
LVVAILFTIS SACYALAALK HQEYLKSSLD VTGTGSGGAL EAQVGEHVVR NVL