ID   TVP18_COCIM             Reviewed;         146 AA.
AC   Q1E1E0; J3KC23;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Golgi apparatus membrane protein TVP18;
GN   Name=TVP18; ORFNames=CIMG_03623;
OS   Coccidioides immitis (strain RS) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=246410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=RS;
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG704916; EAS32599.3; -; Genomic_DNA.
DR   RefSeq; XP_001244182.1; XM_001244181.2.
DR   AlphaFoldDB; Q1E1E0; -.
DR   STRING; 246410.Q1E1E0; -.
DR   EnsemblFungi; EAS32599; EAS32599; CIMG_03623.
DR   GeneID; 4563641; -.
DR   KEGG; cim:CIMG_03623; -.
DR   VEuPathDB; FungiDB:CIMG_03623; -.
DR   InParanoid; Q1E1E0; -.
DR   OMA; ETNYMRA; -.
DR   OrthoDB; 1497869at2759; -.
DR   Proteomes; UP000001261; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019365; TVP18/Ca-channel_flower.
DR   PANTHER; PTHR13314; PTHR13314; 1.
DR   Pfam; PF10233; Cg6151-P; 1.
DR   SMART; SM01077; Cg6151-P; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..146
FT                   /note="Golgi apparatus membrane protein TVP18"
FT                   /id="PRO_0000343018"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        11
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   146 AA;  16027 MW;  AC503547E4ABC4CE CRC64;
     MSLAEEFKSR NFSIYGQWTG VICIILSFAI GLASVFSRFI VFGIISLVYS PLLLFIEVPF
     LLRICPTSSK FDAFIRRFTT NFMRAAIYAA MSGGLWISLV IDPSSLIAVA VFLAIAGLFY
     LLAALMKQEF TSSKTLGGQG VAQMIV