TVP18_KLULA
ID TVP18_KLULA Reviewed; 171 AA.
AC Q6CMQ1;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Golgi apparatus membrane protein TVP18;
GN Name=TVP18; OrderedLocusNames=KLLA0E18623g;
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
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DR EMBL; CR382125; CAG99875.1; -; Genomic_DNA.
DR RefSeq; XP_454788.1; XM_454788.1.
DR AlphaFoldDB; Q6CMQ1; -.
DR STRING; 28985.XP_454788.1; -.
DR EnsemblFungi; CAG99875; CAG99875; KLLA0_E18525g.
DR GeneID; 2894479; -.
DR KEGG; kla:KLLA0_E18525g; -.
DR eggNOG; ENOG502S3AC; Eukaryota.
DR HOGENOM; CLU_118698_1_0_1; -.
DR InParanoid; Q6CMQ1; -.
DR OMA; ETNYMRA; -.
DR Proteomes; UP000000598; Chromosome E.
DR GO; GO:0030173; C:integral component of Golgi membrane; IEA:EnsemblFungi.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:EnsemblFungi.
DR InterPro; IPR019365; TVP18/Ca-channel_flower.
DR PANTHER; PTHR13314; PTHR13314; 1.
DR Pfam; PF10233; Cg6151-P; 1.
DR SMART; SM01077; Cg6151-P; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..171
FT /note="Golgi apparatus membrane protein TVP18"
FT /id="PRO_0000343020"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 12
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 24
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 171 AA; 18624 MW; A5FB362B09AFB428 CRC64;
MVSVGFLKSM FNVSGMVADL KSSNFSIYGQ WISYLNIIFC LAFGIANIFH FSAVIVFSII
AIVQGLIILF IEVPFLLKIC PLSDNFIGFV SKFDTNLRRA LFYLVMCAIQ WCSIIVQSTS
LIVVAVGLSI TATVYALGAA AGQEFKNSAI LSDRGRVAAS VTNEAVVRDM L