TVP18_PICGU
ID TVP18_PICGU Reviewed; 172 AA.
AC A5DEQ7;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Golgi apparatus membrane protein TVP18;
GN Name=TVP18; ORFNames=PGUG_01758;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408156; EDK37660.2; -; Genomic_DNA.
DR RefSeq; XP_001486087.1; XM_001486037.1.
DR AlphaFoldDB; A5DEQ7; -.
DR STRING; 4929.XP_001486087.1; -.
DR EnsemblFungi; EDK37660; EDK37660; PGUG_01758.
DR GeneID; 5127888; -.
DR KEGG; pgu:PGUG_01758; -.
DR VEuPathDB; FungiDB:PGUG_01758; -.
DR eggNOG; ENOG502S3AC; Eukaryota.
DR HOGENOM; CLU_118698_0_0_1; -.
DR InParanoid; A5DEQ7; -.
DR OMA; ETNYMRA; -.
DR OrthoDB; 1497869at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019365; TVP18/Ca-channel_flower.
DR PANTHER; PTHR13314; PTHR13314; 1.
DR Pfam; PF10233; Cg6151-P; 1.
DR SMART; SM01077; Cg6151-P; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..172
FT /note="Golgi apparatus membrane protein TVP18"
FT /id="PRO_0000343026"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 24
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 172 AA; 19056 MW; 1227F34062D15FC7 CRC64;
MALSISTVMS NVFGGFSADF KKKNFSLYGQ WIGLFTIILC LALGIANIFH ASLVIIFSII
CIVQGLVVVF VEVPFLLRIC PLTDKFTSFI KNFDENWPRC GFYLLMSVIQ WLSLTLQTTS
LIVVAVFFAL ASACYALAAI KHQEYLKTSF NVAGEQGSLE AQVGEHVVRN VL
