TVP18_YEAS7
ID TVP18_YEAS7 Reviewed; 167 AA.
AC A6ZMD0;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=Golgi apparatus membrane protein TVP18;
DE AltName: Full=TLG2 compartment vesicle protein of 18 kDa;
GN Name=TVP18; ORFNames=SCY_4242;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with TVP15 and YIP4. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP18 family. {ECO:0000305}.
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DR EMBL; AAFW02000020; EDN64460.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZMD0; -.
DR EnsemblFungi; EDN64460; EDN64460; SCY_4242.
DR HOGENOM; CLU_118698_1_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019365; TVP18/Ca-channel_flower.
DR PANTHER; PTHR13314; PTHR13314; 1.
DR Pfam; PF10233; Cg6151-P; 1.
DR SMART; SM01077; Cg6151-P; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Phosphoprotein; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..167
FT /note="Golgi apparatus membrane protein TVP18"
FT /id="PRO_0000343029"
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 121..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 146
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q04767"
FT MOD_RES 153
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q04767"
FT CARBOHYD 22
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 167 AA; 18693 MW; 46698DC0400D3097 CRC64;
MALSLGQFIN VGGMVKDLKS FNFSVYGRWF GYINIILCIA LGIANLFHVS GVIAFGIISI
IQGLVILFIE IPFLLKICPL SDNFIEFIKR FETNGWRCLF YLAMAIIQYI SIAVMATSLI
VVAVGLTISS ISYAVAYTKH QEFQNTNIIK NPTDDDFPHE AVVREML