TVP23_NEUCR
ID TVP23_NEUCR Reviewed; 191 AA.
AC Q7SGB6; V5IRI6;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-FEB-2014, sequence version 4.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Golgi apparatus membrane protein tvp23;
GN Name=tvp23; ORFNames=NCU02733;
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP23 family. {ECO:0000305}.
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DR EMBL; CM002236; ESA43966.1; -; Genomic_DNA.
DR RefSeq; XP_011393013.1; XM_011394711.1.
DR AlphaFoldDB; Q7SGB6; -.
DR STRING; 5141.EFNCRP00000002120; -.
DR EnsemblFungi; ESA43966; ESA43966; NCU02733.
DR GeneID; 3881258; -.
DR KEGG; ncr:NCU02733; -.
DR VEuPathDB; FungiDB:NCU02733; -.
DR HOGENOM; CLU_074845_1_0_1; -.
DR InParanoid; Q7SGB6; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR InterPro; IPR008564; TVP23-like.
DR PANTHER; PTHR13019; PTHR13019; 1.
DR Pfam; PF05832; DUF846; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..191
FT /note="Golgi apparatus membrane protein tvp23"
FT /id="PRO_0000343051"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 103
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 191 AA; 21280 MW; 4FA5342C732C74EB CRC64;
MMEATPTPGS LSWRLSSHPI TLLTFLAFRS SSLLVYLFGL LFTDNLVMIF IITILLLAGD
FYYLKNIAGR RLVGLRWWNE VDPNSGDSHW VFESSEPGTK IINATDSRFF WLAIYAQPLL
WVVLAIVALF SLKFIWLPLV AIALVLTITN SLAFSRCDKF SQASNIAGTA FSSGNIAGNI
ASNMVGRFFS R