TVP23_PICGU
ID TVP23_PICGU Reviewed; 236 AA.
AC A5DRE8;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Golgi apparatus membrane protein TVP23;
GN Name=TVP23; ORFNames=PGUG_05849;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TVP23 family. {ECO:0000305}.
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DR EMBL; CH408162; EDK41751.2; -; Genomic_DNA.
DR RefSeq; XP_001482086.1; XM_001482036.1.
DR AlphaFoldDB; A5DRE8; -.
DR STRING; 4929.XP_001482086.1; -.
DR EnsemblFungi; EDK41751; EDK41751; PGUG_05849.
DR GeneID; 5123922; -.
DR KEGG; pgu:PGUG_05849; -.
DR VEuPathDB; FungiDB:PGUG_05849; -.
DR eggNOG; KOG3195; Eukaryota.
DR HOGENOM; CLU_074845_0_0_1; -.
DR InParanoid; A5DRE8; -.
DR OMA; ICPVIWI; -.
DR OrthoDB; 1356321at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR008564; TVP23-like.
DR PANTHER; PTHR13019; PTHR13019; 1.
DR Pfam; PF05832; DUF846; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..236
FT /note="Golgi apparatus membrane protein TVP23"
FT /id="PRO_0000343053"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 236 AA; 26574 MW; B525AC21EAE05E5A CRC64;
MSSQYTAIES DVPQAQPAGA TGPMDNQMGG EPNSGQINSD PSSWTWIQRL KQSSHPVALL
FYIGFRILPI EIYIFGNFFI GFITKKNRFI LHFIVLVLLI SGDFWNLKNV AGRLLVGLRW
WNEVNFIESS STGEFENVWV FESADPSRYI NPIDSKVFWT LLYGQPVAWI VLGILAVLKF
EFLYLILILI AIFLSFTNAL AFTKCDKFGK ANNLATGFLS RASGTILSRL NPFASR