ID   TVP38_ASPFC             Reviewed;         418 AA.
AC   B0Y4Q5;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Golgi apparatus membrane protein tvp38;
GN   Name=tvp38; ORFNames=AFUB_069910;
OS   Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus
OS   fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=451804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CEA10 / CBS 144.89 / FGSC A1163;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; DS499598; EDP50654.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0Y4Q5; -.
DR   EnsemblFungi; EDP50654; EDP50654; AFUB_069910.
DR   VEuPathDB; FungiDB:AFUB_069910; -.
DR   HOGENOM; CLU_041954_0_0_1; -.
DR   PhylomeDB; B0Y4Q5; -.
DR   Proteomes; UP000001699; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..418
FT                   /note="Golgi apparatus membrane protein tvp38"
FT                   /id="PRO_0000343061"
FT   TOPO_DOM        1..81
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        103..119
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..157
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        181..234
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        256..273
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        295..418
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          149..258
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
FT   REGION          367..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  46734 MW;  FF50761C7F3D511B CRC64;
     MPADYTSTAR ALSLPMSPAE SLSPAEEDTR PLWSHLASSR RNTASPSVRE STGLRDQVVN
     QATKMLRRTK KTWRRLTFWQ RIGAIGAALL AILLGLSFMI FTGQVFFWLG PVAEKWEQSW
     LAFFVLWLCV FFVSFPPLVG WSTFGTISGF IYGIWKGWIL YATATVLGST CSFIVSRTIL
     SKFVNRMMER DKRFAALALT LKYDGLKLLC MIRLCPLPYS VCNGAVSTFP TVHPLMYGLA
     TALITPKLLV PAFIGSRIRI LSEKNEEMSA ASKAVNICSI ILTIGIGVFT GWYIYRRTLA
     RAKELEAKER ADIRRSLQAD HAAHRPHGSF SEDPDVNTAA TTLARDEEER IGFNDFDDDN
     VDLVIDDDSG SEISPNLTKK QFPGPYRDEF TDNDSDVFGD GDGPDSQMFR LHTHVRSG