ID   TVP38_ASPTN             Reviewed;         418 AA.
AC   Q0CT01;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Golgi apparatus membrane protein tvp38;
GN   Name=tvp38; ORFNames=ATEG_03183;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; CH476597; EAU36457.1; -; Genomic_DNA.
DR   RefSeq; XP_001212361.1; XM_001212361.1.
DR   AlphaFoldDB; Q0CT01; -.
DR   STRING; 341663.Q0CT01; -.
DR   EnsemblFungi; EAU36457; EAU36457; ATEG_03183.
DR   GeneID; 4317830; -.
DR   VEuPathDB; FungiDB:ATEG_03183; -.
DR   eggNOG; KOG3140; Eukaryota.
DR   HOGENOM; CLU_041954_0_0_1; -.
DR   OMA; YHDEFTD; -.
DR   OrthoDB; 1327131at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..418
FT                   /note="Golgi apparatus membrane protein tvp38"
FT                   /id="PRO_0000343064"
FT   TOPO_DOM        1..82
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        104..121
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        143..158
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        182..235
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        257..274
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        296..418
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..259
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
FT   REGION          368..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..28
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..406
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        65
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   418 AA;  46821 MW;  68536D07BB0E695D CRC64;
     MPADYTSTAR ALSLSTSPPL SSPTSEDGSY LPWRHLAPTG RRDSSSRSIR ESNSLRHQVM
     NRINNASQRI IMTWRRMNFW QRIGAVLAAI LANLLGIGFL VFTGKVFIWL KPVAEQWEHN
     PLVFFVLWLC VFFVSFPPLV GWSTFGTVAG YIFGVWKGWL LYASATVLGS TASFIVSRTI
     LSKFVHRLME RDKRFAALAL TLKYDGLKLL CMIRLCPLPY SVCNGAVSTF PTVHPLTYGL
     ATAIITPKLL VPAFIGNRLR VLSEKGGEMS AGSKAVNICS IIITIAIGIF TGWYIYRRTL
     ARAKELEAQE REGIRQSLEA DHAAHRPHHA FFEDPEANIA ATTLACDEEE RIGFHDFDDD
     NVDLVLDDES GREISPKRTD GPYRDEFTDN DSDVFKDGDG TDGETYTLHT HVRQNPRS