ID   TVP38_CANGA             Reviewed;         323 AA.
AC   Q6FTI0;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Golgi apparatus membrane protein TVP38;
GN   Name=TVP38; OrderedLocusNames=CAGL0G02343g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; CR380953; CAG59391.1; -; Genomic_DNA.
DR   RefSeq; XP_446464.1; XM_446464.1.
DR   AlphaFoldDB; Q6FTI0; -.
DR   SMR; Q6FTI0; -.
DR   STRING; 5478.XP_446464.1; -.
DR   EnsemblFungi; CAG59391; CAG59391; CAGL0G02343g.
DR   GeneID; 2888032; -.
DR   KEGG; cgr:CAGL0G02343g; -.
DR   CGD; CAL0137539; CAGL0G02343g.
DR   VEuPathDB; FungiDB:CAGL0G02343g; -.
DR   eggNOG; KOG3140; Eukaryota.
DR   HOGENOM; CLU_041954_1_1_1; -.
DR   InParanoid; Q6FTI0; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IEA:EnsemblFungi.
DR   GO; GO:0000022; P:mitotic spindle elongation; IEA:EnsemblFungi.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:EnsemblFungi.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..323
FT                   /note="Golgi apparatus membrane protein TVP38"
FT                   /id="PRO_0000343066"
FT   TOPO_DOM        1..81
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        103..123
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        145..148
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        170..237
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        259..272
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        294..323
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          149..260
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
SQ   SEQUENCE   323 AA;  36739 MW;  C7E5C308D858B9C5 CRC64;
     MPTDNADLGQ EDIDVFDNGR ESFDRLNKPV LDGIGIEGND DDDDDYLTLY NMTPRERLMY
     TFRRSMYKAL DHFNSLPKWQ RLLIILFGAL VIVLGILMLI FHNKILDKVL ETSKDLNERS
     STNFILLVLL FFVGFPPMIG YSFLSTSTGL IYGVSFHGWF VLALGSVTGS VASFYVFKNL
     LHSRAEKLVH MNKRFEAFAS ILQEDNSYLM LALLRLCPFP YSLTNGAIAG IYGISVKNFT
     IANIITTPKL LIYLFIGARI KNMAEDHSTS SRIFDLVSIL ITLIIFTLTA WLLYFKTKQR
     YAQLKNQAVA QNSSANREVD FEI