ID   TVP38_COPC7             Reviewed;         294 AA.
AC   A8NX72;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Golgi apparatus membrane protein TVP38;
GN   Name=TVP38; ORFNames=CC1G_00221;
OS   Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)
OS   (Inky cap fungus) (Hormographiella aspergillata).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Psathyrellaceae; Coprinopsis.
OX   NCBI_TaxID=240176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003;
RX   PubMed=20547848; DOI=10.1073/pnas.1003391107;
RA   Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., Borodovsky M.,
RA   Burns C., Canbaeck B., Casselton L.A., Cheng C.K., Deng J., Dietrich F.S.,
RA   Fargo D.C., Farman M.L., Gathman A.C., Goldberg J., Guigo R., Hoegger P.J.,
RA   Hooker J.B., Huggins A., James T.Y., Kamada T., Kilaru S., Kodira C.,
RA   Kuees U., Kupfer D., Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.-J.,
RA   Mackey A.J., Manning G., Martin F., Muraguchi H., Natvig D.O.,
RA   Palmerini H., Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M.,
RA   Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q.,
RA   Zolan M.E., Pukkila P.J.;
RT   "Insights into evolution of multicellular fungi from the assembled
RT   chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus).";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; AACS02000005; EAU84702.1; -; Genomic_DNA.
DR   RefSeq; XP_001837085.1; XM_001837033.1.
DR   AlphaFoldDB; A8NX72; -.
DR   STRING; 5346.XP_001837085.1; -.
DR   EnsemblFungi; EAU84702; EAU84702; CC1G_00221.
DR   GeneID; 6013641; -.
DR   KEGG; cci:CC1G_00221; -.
DR   VEuPathDB; FungiDB:CC1G_00221; -.
DR   eggNOG; KOG3140; Eukaryota.
DR   HOGENOM; CLU_041954_2_0_1; -.
DR   InParanoid; A8NX72; -.
DR   OMA; KWQALET; -.
DR   OrthoDB; 1327131at2759; -.
DR   Proteomes; UP000001861; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..294
FT                   /note="Golgi apparatus membrane protein TVP38"
FT                   /id="PRO_0000343067"
FT   TOPO_DOM        1..34
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        56..74
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        96..112
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        134..187
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        209..229
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        251..294
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          103..212
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
SQ   SEQUENCE   294 AA;  32964 MW;  E714E5882D8B642C CRC64;
     MAADSTPGSH HRNLFFQYGK AAIHRYHRLH LYGKAFIWLV ILFYIAFGVF VIIVTPARIA
     QFLYDQAKLL AATRFGWVAL LLSIICISFP PLIGHTTLVT LCGFAYGMKG FYIAFAGSIL
     GSALVFVVLR FLFTEKIRSW SAQNEKWQAL EAVVRSKGLP LIVLIRVSPF PPWVYANSLF
     ASIEPVKLWQ FVAATCFITP KLLLYVFMGS KMAALSDGDQ RDRMDTHDKI INGLFLAGSL
     VIAVFTSWLV YNLVQNHIRH LHGVDPETDE LAAEAIEDFD EDAPLLSPTA SHRV