ID   TVP38_PODAN             Reviewed;         378 AA.
AC   B2AMJ3; A0A090CMY0;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Golgi apparatus membrane protein TVP38;
GN   Name=TVP38; OrderedLocusNames=Pa_5_6980; ORFNames=PODANS_5_6980;
OS   Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)
OS   (Pleurage anserina).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Podosporaceae; Podospora;
OC   Podospora anserina.
OX   NCBI_TaxID=515849;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383;
RX   PubMed=18460219; DOI=10.1186/gb-2008-9-5-r77;
RA   Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., Porcel B.M.,
RA   Couloux A., Aury J.-M., Segurens B., Poulain J., Anthouard V.,
RA   Grossetete S., Khalili H., Coppin E., Dequard-Chablat M., Picard M.,
RA   Contamine V., Arnaise S., Bourdais A., Berteaux-Lecellier V., Gautheret D.,
RA   de Vries R.P., Battaglia E., Coutinho P.M., Danchin E.G.J., Henrissat B.,
RA   El Khoury R., Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H.,
RA   Debuchy R., Wincker P., Weissenbach J., Silar P.;
RT   "The genome sequence of the model ascomycete fungus Podospora anserina.";
RL   Genome Biol. 9:R77.1-R77.22(2008).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383;
RX   PubMed=24558260; DOI=10.1534/genetics.113.159988;
RA   Grognet P., Bidard F., Kuchly C., Tong L.C.H., Coppin E., Benkhali J.A.,
RA   Couloux A., Wincker P., Debuchy R., Silar P.;
RT   "Maintaining two mating types: Structure of the mating type locus and its
RT   role in heterokaryosis in Podospora anserina.";
RL   Genetics 197:421-432(2014).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; CU633870; CAP65116.1; -; Genomic_DNA.
DR   EMBL; FO904940; CDP29795.1; -; Genomic_DNA.
DR   RefSeq; XP_001905208.1; XM_001905173.1.
DR   AlphaFoldDB; B2AMJ3; -.
DR   SMR; B2AMJ3; -.
DR   STRING; 5145.XP_001905208.1; -.
DR   EnsemblFungi; CAP65116; CAP65116; PODANS_5_6980.
DR   GeneID; 6189338; -.
DR   KEGG; pan:PODANSg2231; -.
DR   VEuPathDB; FungiDB:PODANS_5_6980; -.
DR   eggNOG; KOG3140; Eukaryota.
DR   HOGENOM; CLU_021545_0_0_1; -.
DR   OrthoDB; 1371054at2759; -.
DR   Proteomes; UP000001197; Chromosome 5.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..378
FT                   /note="Golgi apparatus membrane protein TVP38"
FT                   /id="PRO_0000343073"
FT   TOPO_DOM        1..37
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..99
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..123
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        145..213
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        235..249
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        271..378
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          130..238
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
FT   REGION          322..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..365
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   378 AA;  42017 MW;  D6C1DD1DF6E2F459 CRC64;
     MGPDEIEMVP PKTPRGLPPS ETDYQPVNWK RLFLRPKYLA MWVVLVIIII LTAIITIYHD
     KVVEVGDIRH FDNVCGGKQE ILTAHPLQHL RPFAEQVRHL PGGWLIPIVI LIVISFPPLF
     GHEIIALLCG VVYGLWIGFG IVAAGTFLGE VGTWFAFKYL FRQKSEKLER TSLSYGALAR
     ITRDGGFWIV LIIRFSAIPT HFSTAVFSTC GVNFWIFAIA TFLTLPKQIF LVYLGVLLLQ
     DKPDDAPKNI VFGIAFVLTI VMAGYIGFKM RFVKKILIEE QEERRKALAM PTMDDTVNTG
     DGVLDTERSE YEALSQNDFS IAMPGPAAGN HTPLGEPSKG PSTAPSGWTT EAVNTPDSPG
     TPPNEYFGQQ PAKGFQWV