ID   TVP38_SCLS1             Reviewed;         393 AA.
AC   A7EFY0;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Golgi apparatus membrane protein tvp38;
GN   Name=tvp38; ORFNames=SS1G_04221;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Golgi membrane protein involved in vesicular trafficking and
CC       spindle migration.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane; Multi-pass membrane
CC       protein.
CC   -!- DOMAIN: The VTT domain was previously called the SNARE-assoc domain. As
CC       there is no evidence that this domain associates with SNARE proteins,
CC       it was renamed as VMP1, TMEM41, and TVP38 (VTT) domain.
CC       {ECO:0000250|UniProtKB:P36164}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; CH476625; EDO01746.1; -; Genomic_DNA.
DR   RefSeq; XP_001594414.1; XM_001594364.1.
DR   AlphaFoldDB; A7EFY0; -.
DR   STRING; 665079.A7EFY0; -.
DR   EnsemblFungi; EDO01746; EDO01746; SS1G_04221.
DR   GeneID; 5490759; -.
DR   KEGG; ssl:SS1G_04221; -.
DR   VEuPathDB; FungiDB:sscle_02g018490; -.
DR   eggNOG; KOG3140; Eukaryota.
DR   HOGENOM; CLU_041954_0_0_1; -.
DR   InParanoid; A7EFY0; -.
DR   OMA; YHDEFTD; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0000022; P:mitotic spindle elongation; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..393
FT                   /note="Golgi apparatus membrane protein tvp38"
FT                   /id="PRO_0000343075"
FT   TOPO_DOM        1..88
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        110..125
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        147..164
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        188..241
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        263..279
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        301..393
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          156..265
FT                   /note="VTT domain"
FT                   /evidence="ECO:0000250|UniProtKB:P36164"
FT   REGION          374..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        82
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   393 AA;  42761 MW;  FAC282FAA39316D7 CRC64;
     MPADYSSTAR ALALPISPLE SPPSSPIQHA ERPPWSRRIS SGVRRAYNSA SPYSSQPTTS
     FKDQILRKAD KLQRKCITAW QNLSTLQKCL AIVAAILNIV LVALFLVYQH QIFASLAPFA
     ERWRDLPGGW MILWAMTFVA AFPPLIGYSS TITIAGFVYG VPKGWAIVAT STVAGSTCSF
     LASRTILSTY VHRLVGKDKR FEALALTLKH DGIKILCMIR LCPLPYSLSN AAVATFPTVH
     PLNYALATAL VTPKLFIHVF IGSRLGSLAG NEGMDTSTKM INYASIVIGG GLGATVGYII
     YQRTMARAKE LEIEELEAAN GDVAPGRRVA AEYSDANNDD AALMNDDDIS LWDNTDEPAR
     YTDFVDEDEA NVFASGDLDE EADIGGRGKM TRT