ID   TX13A_HUMAN             Reviewed;         409 AA.
AC   Q9BXU3; B1B1G8; Q32NB6;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Testis-expressed protein 13A;
GN   Name=TEX13A;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=11279525; DOI=10.1038/86927;
RA   Wang P.J., McCarrey J.R., Yang F., Page D.C.;
RT   "An abundance of X-linked genes expressed in spermatogonia.";
RL   Nat. Genet. 27:422-426(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15772651; DOI=10.1038/nature03440;
RA   Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA   Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA   Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA   Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA   Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA   Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA   Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA   Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA   Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA   Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA   Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA   Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA   Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA   Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA   Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA   Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA   Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA   Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA   Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA   Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA   Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA   Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA   Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA   Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA   Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA   Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA   Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA   Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA   Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA   McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA   Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA   Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA   Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA   Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA   Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA   Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA   Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA   Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA   Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA   d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA   Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA   Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA   Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA   Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA   Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA   Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA   Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA   Rogers J., Bentley D.R.;
RT   "The DNA sequence of the human X chromosome.";
RL   Nature 434:325-337(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- INTERACTION:
CC       Q9BXU3; P48047: ATP5PO; NbExp=3; IntAct=EBI-10301068, EBI-355815;
CC       Q9BXU3; A0A024R8L2: hCG_1987119; NbExp=3; IntAct=EBI-10301068, EBI-14103818;
CC       Q9BXU3; Q9BXI6: TBC1D10A; NbExp=6; IntAct=EBI-10301068, EBI-7815040;
CC       Q9BXU3; Q5W5X9-3: TTC23; NbExp=3; IntAct=EBI-10301068, EBI-9090990;
CC       Q9BXU3; P10599: TXN; NbExp=3; IntAct=EBI-10301068, EBI-594644;
CC   -!- TISSUE SPECIFICITY: Testis specific.
CC   -!- SIMILARITY: Belongs to the TEX13 family.
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DR   EMBL; AF285597; AAK31976.1; -; mRNA.
DR   EMBL; Z74477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC042547; AAH42547.1; -; mRNA.
DR   EMBL; BC108734; AAI08735.1; -; mRNA.
DR   CCDS; CCDS76005.1; -.
DR   RefSeq; NP_001278206.1; NM_001291277.1.
DR   RefSeq; NP_112564.1; NM_031274.4.
DR   AlphaFoldDB; Q9BXU3; -.
DR   BMRB; Q9BXU3; -.
DR   SMR; Q9BXU3; -.
DR   BioGRID; 121091; 26.
DR   IntAct; Q9BXU3; 25.
DR   STRING; 9606.ENSP00000471604; -.
DR   iPTMnet; Q9BXU3; -.
DR   PhosphoSitePlus; Q9BXU3; -.
DR   BioMuta; TEX13A; -.
DR   DMDM; 50401671; -.
DR   jPOST; Q9BXU3; -.
DR   MassIVE; Q9BXU3; -.
DR   MaxQB; Q9BXU3; -.
DR   PaxDb; Q9BXU3; -.
DR   PeptideAtlas; Q9BXU3; -.
DR   PRIDE; Q9BXU3; -.
DR   ProteomicsDB; 79520; -.
DR   Antibodypedia; 72864; 108 antibodies from 20 providers.
DR   DNASU; 56157; -.
DR   Ensembl; ENST00000600991.6; ENSP00000471604.2; ENSG00000268629.8.
DR   Ensembl; ENST00000609007.3; ENSP00000477478.2; ENSG00000268629.8.
DR   GeneID; 56157; -.
DR   KEGG; hsa:56157; -.
DR   MANE-Select; ENST00000600991.6; ENSP00000471604.2; NM_031274.5; NP_112564.1.
DR   UCSC; uc033epz.1; human.
DR   CTD; 56157; -.
DR   GeneCards; TEX13A; -.
DR   HGNC; HGNC:11735; TEX13A.
DR   HPA; ENSG00000268629; Tissue enriched (testis).
DR   MIM; 300312; gene.
DR   neXtProt; NX_Q9BXU3; -.
DR   OpenTargets; ENSG00000268629; -.
DR   PharmGKB; PA36452; -.
DR   VEuPathDB; HostDB:ENSG00000268629; -.
DR   eggNOG; KOG4198; Eukaryota.
DR   GeneTree; ENSGT00940000164308; -.
DR   HOGENOM; CLU_736812_0_0_1; -.
DR   InParanoid; Q9BXU3; -.
DR   OMA; VCTEGAG; -.
DR   OrthoDB; 651291at2759; -.
DR   PhylomeDB; Q9BXU3; -.
DR   TreeFam; TF337208; -.
DR   PathwayCommons; Q9BXU3; -.
DR   SignaLink; Q9BXU3; -.
DR   BioGRID-ORCS; 56157; 10 hits in 275 CRISPR screens.
DR   GenomeRNAi; 56157; -.
DR   Pharos; Q9BXU3; Tdark.
DR   PRO; PR:Q9BXU3; -.
DR   Proteomes; UP000005640; Chromosome X.
DR   RNAct; Q9BXU3; protein.
DR   Bgee; ENSG00000268629; Expressed in sperm and 15 other tissues.
DR   Genevisible; Q9BXU3; HS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   InterPro; IPR028193; TEX13.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   Pfam; PF15186; TEX13; 1.
DR   SUPFAM; SSF90209; SSF90209; 1.
DR   PROSITE; PS01358; ZF_RANBP2_1; 1.
DR   PROSITE; PS50199; ZF_RANBP2_2; 1.
PE   1: Evidence at protein level;
KW   Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..409
FT                   /note="Testis-expressed protein 13A"
FT                   /id="PRO_0000065700"
FT   ZN_FING         376..405
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00322"
FT   REGION          347..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   409 AA;  45583 MW;  6EC20D9DF945299F CRC64;
     MALRPEDPSS GFRHSNVVAF INEKMARHTK GPEFYLENIS LSWEKVEDKL RAILEDSEVP
     SEVKEACTWG SLALGVRFAH RQAQLQRHRV RWLHGFAKLH KSAAQALASD LKKLREQQET
     ERKEAASRLR MAQTSLVEVQ KERDKELVSP HEWEQGAGWP GLATAGGVCT EGAAEEEEEA
     AVAAAGAAGG KGAEEEQRDV EVVAAPVEAM APPVEAGAAP METQFPHVEA RAASMETTEK
     LERILLQLLG DADQEKYTYW GQKEGDLRSV ETATSYFSGT TNPWSRASSE PLPVQLPASY
     SYSYSSPFSS FSDIPTISPP QATVTAPVPP QLPSDWEAFD TSLWSDGGPH RIDHQEHPRD
     RRYSEPHQQR PPVYRRPGDW DCPWCNAVNF SRRDTCFDCG KGIWLQKPH