TX13B_HUMAN
ID TX13B_HUMAN Reviewed; 312 AA.
AC Q9BXU2; Q5JYF6;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Testis-expressed protein 13B;
GN Name=TEX13B;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Testis;
RX PubMed=11279525; DOI=10.1038/86927;
RA Wang P.J., McCarrey J.R., Yang F., Page D.C.;
RT "An abundance of X-linked genes expressed in spermatogonia.";
RL Nat. Genet. 27:422-426(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
CC -!- INTERACTION:
CC Q9BXU2; Q9UM19: HPCAL4; NbExp=3; IntAct=EBI-12007066, EBI-744820;
CC Q9BXU2; P62760: VSNL1; NbExp=8; IntAct=EBI-12007066, EBI-740943;
CC -!- TISSUE SPECIFICITY: Testis specific.
CC -!- SIMILARITY: Belongs to the TEX13 family.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF285598; AAK31977.1; -; mRNA.
DR EMBL; AL034399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS14534.1; -.
DR RefSeq; NP_112563.1; NM_031273.2.
DR AlphaFoldDB; Q9BXU2; -.
DR BioGRID; 121090; 168.
DR IntAct; Q9BXU2; 2.
DR STRING; 9606.ENSP00000303777; -.
DR iPTMnet; Q9BXU2; -.
DR PhosphoSitePlus; Q9BXU2; -.
DR BioMuta; TEX13B; -.
DR DMDM; 50401670; -.
DR jPOST; Q9BXU2; -.
DR MassIVE; Q9BXU2; -.
DR MaxQB; Q9BXU2; -.
DR PaxDb; Q9BXU2; -.
DR PeptideAtlas; Q9BXU2; -.
DR PRIDE; Q9BXU2; -.
DR TopDownProteomics; Q9BXU2; -.
DR Antibodypedia; 29357; 79 antibodies from 18 providers.
DR DNASU; 56156; -.
DR Ensembl; ENST00000302917.1; ENSP00000303777.1; ENSG00000170925.3.
DR GeneID; 56156; -.
DR KEGG; hsa:56156; -.
DR MANE-Select; ENST00000302917.1; ENSP00000303777.1; NM_031273.2; NP_112563.1.
DR UCSC; uc004enn.1; human.
DR CTD; 56156; -.
DR GeneCards; TEX13B; -.
DR HGNC; HGNC:11736; TEX13B.
DR HPA; ENSG00000170925; Not detected.
DR MIM; 300313; gene.
DR neXtProt; NX_Q9BXU2; -.
DR OpenTargets; ENSG00000170925; -.
DR PharmGKB; PA36453; -.
DR VEuPathDB; HostDB:ENSG00000170925; -.
DR eggNOG; ENOG502RWXQ; Eukaryota.
DR GeneTree; ENSGT00940000161342; -.
DR HOGENOM; CLU_080055_0_0_1; -.
DR InParanoid; Q9BXU2; -.
DR OMA; HTHYTPF; -.
DR OrthoDB; 1100997at2759; -.
DR PhylomeDB; Q9BXU2; -.
DR TreeFam; TF337208; -.
DR PathwayCommons; Q9BXU2; -.
DR SignaLink; Q9BXU2; -.
DR BioGRID-ORCS; 56156; 24 hits in 690 CRISPR screens.
DR GenomeRNAi; 56156; -.
DR Pharos; Q9BXU2; Tdark.
DR PRO; PR:Q9BXU2; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; Q9BXU2; protein.
DR Bgee; ENSG00000170925; Expressed in testis and 2 other tissues.
DR Genevisible; Q9BXU2; HS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR InterPro; IPR028193; TEX13.
DR Pfam; PF15186; TEX13; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..312
FT /note="Testis-expressed protein 13B"
FT /id="PRO_0000065701"
SQ SEQUENCE 312 AA; 33967 MW; 5AF95FA554530638 CRC64;
MALRPEDPSS GFRHGNVVAF IIEKMARHTK GPEFYFENIS LSWEEVEDKL RAILEDSEVP
SEVKEACTWG SLALGVRFAH RQGQLQNRRV QWLQGFAKLH RSAALVLASN LTELKEQQEM
ECNEATFQLQ LTETSLAEVQ RERDMLRWKL FHAELAPPQG QGQATVFPGL ATAGGDWTEG
AGEQEKEAVA AAGAAGGKGE ERYAEAGPAP AEVLQGLGGG FRQPLGAIVA GKLHLCGAEG
ERSQVSTNSH VCLLWAWVHS LTGASSCPAP YLIHILIPMP FVRLLSHTQY TPFTSKGHRT
GSNSDAFQLG GL