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TX13C_HUMAN
ID   TX13C_HUMAN             Reviewed;         993 AA.
AC   A0A0J9YWL9;
DT   13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2015, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Putative testis-expressed protein 13C {ECO:0000305};
GN   Name=TEX13C {ECO:0000312|HGNC:HGNC:52277};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15772651; DOI=10.1038/nature03440;
RA   Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA   Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA   Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA   Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA   Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA   Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA   Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA   Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA   Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA   Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA   Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA   Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA   Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA   Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA   Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA   Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA   Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA   Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA   Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA   Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA   Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA   Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA   Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA   Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA   Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA   Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA   Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA   Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA   Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA   McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA   Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA   Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA   Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA   Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA   Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA   Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA   Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA   Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA   Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA   d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA   Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA   Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA   Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA   Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA   Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA   Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA   Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA   Rogers J., Bentley D.R.;
RT   "The DNA sequence of the human X chromosome.";
RL   Nature 434:325-337(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TEX13 family.
CC   -!- CAUTION: Could be the product of a pseudogene. This gene is longer than
CC       the rat and mouse orthologs and also contains a RanBP2-type zinc finger
CC       which is not present in those orthologs. {ECO:0000305}.
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DR   EMBL; AL627231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471107; EAX11844.1; -; Genomic_DNA.
DR   CCDS; CCDS83488.1; -.
DR   RefSeq; NP_001182201.1; NM_001195272.1.
DR   RefSeq; XP_005262409.1; XM_005262352.3.
DR   AlphaFoldDB; A0A0J9YWL9; -.
DR   IntAct; A0A0J9YWL9; 1.
DR   GlyGen; A0A0J9YWL9; 1 site, 1 O-linked glycan (1 site).
DR   iPTMnet; A0A0J9YWL9; -.
DR   PhosphoSitePlus; A0A0J9YWL9; -.
DR   BioMuta; TEX13C; -.
DR   jPOST; A0A0J9YWL9; -.
DR   MassIVE; A0A0J9YWL9; -.
DR   PeptideAtlas; A0A0J9YWL9; -.
DR   Ensembl; ENST00000632600.1; ENSP00000488022.1; ENSG00000282815.1.
DR   GeneID; 100129520; -.
DR   KEGG; hsa:100129520; -.
DR   CTD; 100129520; -.
DR   GeneCards; TEX13C; -.
DR   HGNC; HGNC:52277; TEX13C.
DR   HPA; ENSG00000282815; Tissue enriched (testis).
DR   neXtProt; NX_A0A0J9YWL9; -.
DR   VEuPathDB; HostDB:ENSG00000282815; -.
DR   GeneTree; ENSGT00940000161768; -.
DR   OMA; QKEDPVM; -.
DR   OrthoDB; 671563at2759; -.
DR   BioGRID-ORCS; 100129520; 7 hits in 156 CRISPR screens.
DR   GenomeRNAi; 100129520; -.
DR   Pharos; A0A0J9YWL9; Tdark.
DR   Proteomes; UP000005640; Chromosome X.
DR   RNAct; A0A0J9YWL9; protein.
DR   Bgee; ENSG00000282815; Expressed in right testis and 2 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   InterPro; IPR028193; TEX13.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   Pfam; PF15186; TEX13; 1.
DR   PROSITE; PS01358; ZF_RANBP2_1; 1.
PE   5: Uncertain;
KW   Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..993
FT                   /note="Putative testis-expressed protein 13C"
FT                   /id="PRO_0000435874"
FT   ZN_FING         955..984
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00322"
FT   REGION          281..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          520..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          894..959
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        308..340
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        896..912
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        931..945
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   993 AA;  109806 MW;  DF334702C1F9FF59 CRC64;
     MAMNFGDHAS GFRHDDVIRF INNEVLRNGG SPAFYTAFRS RPWNEVEDRL RAIVADPRVP
     RAIKRACTWS ALALSVQVAA RQQEELLYQV WWLQGHVEEC QATSWALTSQ LQQLRLEHEE
     VATQLHLTQA ALQQVLNERD GLCGRLLEVE RSMQVYPMPQ DFVPGPEAGQ YGPVAGTLNA
     EQSEAVATEA QGMPHSEAQV AAPTAVYYMP EPQSGRVQGM QPLLLMQAPH PVPFHMPSPM
     GLPYSTPLPP PVVMESAAAI APQMPPAGIY PPGLWATVGS QEETAPPWDQ KCHGQDGYPE
     NFQGVYHPGD NRSCNQKEGS ECPQGMTSQG DSSSHSLKKD PVMQEGTAPP EFSRSHSLEK
     KPVMPKEMVP LGDSNSHSLK KDPVVPKEIV PIGDSNSHSL TKNPVVHKEM VSLGDSNSHS
     MKKDPVMPQK MVPLGDSNSH SLKKDPMMCQ EMVPLGDSNS HSLKKDPVVA QGTAPLMYSR
     RHSQKKVPMM PKEMVPLGES HSHSLKKDLV VPKELVPLGD SKSHRMKKDP VMPQKMVPLG
     DSRSHSLKKD PVMPQNMIPL EDSNSHSLKK DPVMPQNMIP LEDSNSHSLK KDPMMHQEMV
     PLGDSNSHSL KKDPVVPQDT APLMFSRRHS LKKVPVMPKE MVPLGDSHSL KKDPVMPQNM
     VPLEDSNSHS LKKDPVVPQG TAPLMFSRRH SLKKVPVMPK EMVPLGDSNS HSLKKDPVVP
     QGTAPLMFSR RHSLKKVPVM PKEMVPLGDS HSLKKDPVMP QNMVPLEDSN SHSLKKDPVV
     PQGTAPLTFS RRHSLKKVPV VPQGTASLGF SRIHSLKKEL VMPEEMVPLG DSNSHSMKKD
     LVMPKEMVPL GDSNSHSLKK DPVVHQEVVS LGDSNSHSLK KHPVIPQGTA SLRFSKSHSQ
     KEDQERPQVT PLEDSKSHGV KNSPWKHQPQ GQKVKEQKRK KASESQQQKP ASCSSPVNWA
     CPWCNAMNFP RNKVCSKCKR VRMPVENGSV DPA
 
 
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