TX13C_HUMAN
ID TX13C_HUMAN Reviewed; 993 AA.
AC A0A0J9YWL9;
DT 13-APR-2016, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2015, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Putative testis-expressed protein 13C {ECO:0000305};
GN Name=TEX13C {ECO:0000312|HGNC:HGNC:52277};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TEX13 family.
CC -!- CAUTION: Could be the product of a pseudogene. This gene is longer than
CC the rat and mouse orthologs and also contains a RanBP2-type zinc finger
CC which is not present in those orthologs. {ECO:0000305}.
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DR EMBL; AL627231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471107; EAX11844.1; -; Genomic_DNA.
DR CCDS; CCDS83488.1; -.
DR RefSeq; NP_001182201.1; NM_001195272.1.
DR RefSeq; XP_005262409.1; XM_005262352.3.
DR AlphaFoldDB; A0A0J9YWL9; -.
DR IntAct; A0A0J9YWL9; 1.
DR GlyGen; A0A0J9YWL9; 1 site, 1 O-linked glycan (1 site).
DR iPTMnet; A0A0J9YWL9; -.
DR PhosphoSitePlus; A0A0J9YWL9; -.
DR BioMuta; TEX13C; -.
DR jPOST; A0A0J9YWL9; -.
DR MassIVE; A0A0J9YWL9; -.
DR PeptideAtlas; A0A0J9YWL9; -.
DR Ensembl; ENST00000632600.1; ENSP00000488022.1; ENSG00000282815.1.
DR GeneID; 100129520; -.
DR KEGG; hsa:100129520; -.
DR CTD; 100129520; -.
DR GeneCards; TEX13C; -.
DR HGNC; HGNC:52277; TEX13C.
DR HPA; ENSG00000282815; Tissue enriched (testis).
DR neXtProt; NX_A0A0J9YWL9; -.
DR VEuPathDB; HostDB:ENSG00000282815; -.
DR GeneTree; ENSGT00940000161768; -.
DR OMA; QKEDPVM; -.
DR OrthoDB; 671563at2759; -.
DR BioGRID-ORCS; 100129520; 7 hits in 156 CRISPR screens.
DR GenomeRNAi; 100129520; -.
DR Pharos; A0A0J9YWL9; Tdark.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; A0A0J9YWL9; protein.
DR Bgee; ENSG00000282815; Expressed in right testis and 2 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR InterPro; IPR028193; TEX13.
DR InterPro; IPR001876; Znf_RanBP2.
DR Pfam; PF15186; TEX13; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
PE 5: Uncertain;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..993
FT /note="Putative testis-expressed protein 13C"
FT /id="PRO_0000435874"
FT ZN_FING 955..984
FT /note="RanBP2-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00322"
FT REGION 281..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 894..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..912
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..945
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 109806 MW; DF334702C1F9FF59 CRC64;
MAMNFGDHAS GFRHDDVIRF INNEVLRNGG SPAFYTAFRS RPWNEVEDRL RAIVADPRVP
RAIKRACTWS ALALSVQVAA RQQEELLYQV WWLQGHVEEC QATSWALTSQ LQQLRLEHEE
VATQLHLTQA ALQQVLNERD GLCGRLLEVE RSMQVYPMPQ DFVPGPEAGQ YGPVAGTLNA
EQSEAVATEA QGMPHSEAQV AAPTAVYYMP EPQSGRVQGM QPLLLMQAPH PVPFHMPSPM
GLPYSTPLPP PVVMESAAAI APQMPPAGIY PPGLWATVGS QEETAPPWDQ KCHGQDGYPE
NFQGVYHPGD NRSCNQKEGS ECPQGMTSQG DSSSHSLKKD PVMQEGTAPP EFSRSHSLEK
KPVMPKEMVP LGDSNSHSLK KDPVVPKEIV PIGDSNSHSL TKNPVVHKEM VSLGDSNSHS
MKKDPVMPQK MVPLGDSNSH SLKKDPMMCQ EMVPLGDSNS HSLKKDPVVA QGTAPLMYSR
RHSQKKVPMM PKEMVPLGES HSHSLKKDLV VPKELVPLGD SKSHRMKKDP VMPQKMVPLG
DSRSHSLKKD PVMPQNMIPL EDSNSHSLKK DPVMPQNMIP LEDSNSHSLK KDPMMHQEMV
PLGDSNSHSL KKDPVVPQDT APLMFSRRHS LKKVPVMPKE MVPLGDSHSL KKDPVMPQNM
VPLEDSNSHS LKKDPVVPQG TAPLMFSRRH SLKKVPVMPK EMVPLGDSNS HSLKKDPVVP
QGTAPLMFSR RHSLKKVPVM PKEMVPLGDS HSLKKDPVMP QNMVPLEDSN SHSLKKDPVV
PQGTAPLTFS RRHSLKKVPV VPQGTASLGF SRIHSLKKEL VMPEEMVPLG DSNSHSMKKD
LVMPKEMVPL GDSNSHSLKK DPVVHQEVVS LGDSNSHSLK KHPVIPQGTA SLRFSKSHSQ
KEDQERPQVT PLEDSKSHGV KNSPWKHQPQ GQKVKEQKRK KASESQQQKP ASCSSPVNWA
CPWCNAMNFP RNKVCSKCKR VRMPVENGSV DPA