TX14A_MYRGU
ID TX14A_MYRGU Reviewed; 67 AA.
AC P0DPU9;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 08-MAY-2019, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=U-myrmeciitoxin(01)-Mg4a {ECO:0000305};
DE Short=MIITX(01)-Mg4a {ECO:0000303|PubMed:30214940};
DE Short=U-MIITX(01)-Mg4a {ECO:0000305};
DE Flags: Precursor;
OS Myrmecia gulosa (Red bulldog ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmeciinae; Myrmeciini; Myrmecia.
OX NCBI_TaxID=36170;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND SUBUNIT.
RC TISSUE=Venom, and Venom gland;
RX PubMed=30214940; DOI=10.1126/sciadv.aau4640;
RA Robinson S.D., Mueller A., Clayton D., Starobova H., Hamilton B.R.,
RA Payne R.J., Vetter I., King G.F., Undheim E.A.B.;
RT "A comprehensive portrait of the venom of the giant red bull ant, Myrmecia
RT gulosa, reveals a hyperdiverse hymenopteran toxin gene family.";
RL Sci. Adv. 4:EAAU4640-EAAU4640(2018).
CC -!- SUBUNIT: Homodimer; disulfide-linked. {ECO:0000269|PubMed:30214940}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30214940}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:30214940}.
CC -!- PTM: Contains 2 intrachain disulfide bonds (one per chain) and 1
CC interchain disulfide bond. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ant myrmeciitoxin-01 family. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC (NCBI);
CC URL="https://www.ncbi.nlm.nih.gov/nuccore/GGFG01000004";
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DR AlphaFoldDB; P0DPU9; -.
DR SMR; P0DPU9; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..25
FT /evidence="ECO:0000269|PubMed:30214940"
FT CHAIN 26..67
FT /note="U-myrmeciitoxin(01)-Mg4a"
FT /evidence="ECO:0000269|PubMed:30214940"
FT /id="PRO_0000447072"
SQ SEQUENCE 67 AA; 7348 MW; F0674D618D94BA39 CRC64;
MGKVFFFVLM IAIIGSTFLI EEALGSLVGC PRPDFLPSWN RCKSCVCKNN KLKCPKILKG
SLLKTAA