ID   TX150_BUNCI             Reviewed;          45 AA.
AC   P86468;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 1.
DT   25-MAY-2022, entry version 20.
DE   RecName: Full=Toxin Bcs III 15.09 {ECO:0000303|Ref.1};
DE   Flags: Fragment;
OS   Bunodosoma caissarum (Sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Actiniidae; Bunodosoma.
OX   NCBI_TaxID=31165;
RN   [1]
RP   PROTEIN SEQUENCE, MASS SPECTROMETRY, AND VARIANT ASP-17.
RC   TISSUE=Venom;
RA   Zaharenko A.J., Ferreira W.A. Jr., Madio B., Orts D.J.B., Oliveira J.S.,
RA   Konno K., Richardson M., Freitas J.C.;
RL   Submitted (FEB-2010) to UniProtKB.
CC   -!- FUNCTION: Has both toxic and EGF activity.
CC       {ECO:0000250|UniProtKB:Q76CA1}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}. Nematocyst {ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=5464.88; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the EGF domain peptide family. {ECO:0000305}.
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DR   AlphaFoldDB; P86468; -.
DR   SMR; P86468; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042151; C:nematocyst; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000742; EGF-like_dom.
DR   Pfam; PF00008; EGF; 1.
DR   SMART; SM00181; EGF; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; EGF-like domain; Nematocyst;
KW   Secreted; Toxin.
FT   CHAIN           1..>45
FT                   /note="Toxin Bcs III 15.09"
FT                   /id="PRO_0000392951"
FT   DOMAIN          2..44
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        6..21
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        15..32
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        34..43
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   VARIANT         17
FT                   /note="N -> D"
FT                   /evidence="ECO:0000269|Ref.1"
FT   NON_TER         45
SQ   SEQUENCE   45 AA;  4961 MW;  59A17237AB5DB0D3 CRC64;
     DQGTACTGEH AHNFCLNGGT CRHIQSLGEY YCICPEGYTG HRCEK