ID   ACBP2_SACMO             Reviewed;          87 AA.
AC   P61868; Q92272; Q96496;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Acyl-CoA-binding protein 2;
DE   AltName: Full=ACBP type 2;
GN   Name=ACB2;
OS   Saccharomyces pastorianus (strain ATCC 76670 / Carlsberg bottom yeast no.2
OS   / CBS 1503 / CLIB 180 / NBRC 10610 / NRRL Y-1525) (Saaz-type lager yeast)
OS   (Saccharomyces monacensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=1429090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 76670 / Carlsberg bottom yeast no.2 / CBS 1503 / CLIB 180 /
RC   NBRC 10610 / NRRL Y-1525;
RX   PubMed=9434347;
RX   DOI=10.1002/(sici)1097-0061(199712)13:15<1409::aid-yea188>3.0.co;2-a;
RA   Borsting C., Hummel R., Schultz E.R., Rose T.M., Pedersen M.B., Knudsen J.,
RA   Kristiansen K.;
RT   "Saccharomyces carlsbergensis contains two functional genes encoding the
RT   acyl-CoA binding protein, one similar to the ACB1 gene from S. cerevisiae
RT   and one identical to the ACB1 gene from S. monacensis.";
RL   Yeast 13:1409-1421(1997).
CC   -!- FUNCTION: Binds medium- and long-chain acyl-CoA esters with very high
CC       affinity and may function as an intracellular carrier of acyl-CoA
CC       esters. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ACBP family. {ECO:0000305}.
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DR   EMBL; Y08688; CAA69946.1; -; Genomic_DNA.
DR   AlphaFoldDB; P61868; -.
DR   SMR; P61868; -.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.80.10; -; 1.
DR   InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR   InterPro; IPR000582; Acyl-CoA-binding_protein.
DR   InterPro; IPR035984; Acyl-CoA-binding_sf.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   Pfam; PF00887; ACBP; 1.
DR   PRINTS; PR00689; ACOABINDINGP.
DR   SUPFAM; SSF47027; SSF47027; 1.
DR   PROSITE; PS00880; ACB_1; 1.
DR   PROSITE; PS51228; ACB_2; 1.
PE   3: Inferred from homology;
KW   Lipid-binding; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..87
FT                   /note="Acyl-CoA-binding protein 2"
FT                   /id="PRO_0000214014"
FT   DOMAIN          2..87
FT                   /note="ACB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00573"
FT   BINDING         29..33
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         51
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         55
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
FT   BINDING         74
FT                   /ligand="an acyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:58342"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   87 AA;  10084 MW;  AB6D04C039EC02EE CRC64;
     MVSQLFEEKA KAVNELPTKP STDELLELYG LYKQATVGDN DKEKPGIFNM KDRYKWEAWE
     DLKGKSQEDA EKEYIAYVDN LIAKYSS