TX18B_MYRGU
ID TX18B_MYRGU Reviewed; 111 AA.
AC P0DSK6;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 08-MAY-2019, sequence version 1.
DT 25-MAY-2022, entry version 5.
DE RecName: Full=U-myrmeciitoxin(01)-Mg8b {ECO:0000305};
DE Short=MIITX(01)-Mg8b {ECO:0000303|PubMed:30214940};
DE Short=U-MIITX(01)-Mg8b {ECO:0000305};
DE Flags: Precursor;
OS Myrmecia gulosa (Red bulldog ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmeciinae; Myrmeciini; Myrmecia.
OX NCBI_TaxID=36170;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=30214940; DOI=10.1126/sciadv.aau4640;
RA Robinson S.D., Mueller A., Clayton D., Starobova H., Hamilton B.R.,
RA Payne R.J., Vetter I., King G.F., Undheim E.A.B.;
RT "A comprehensive portrait of the venom of the giant red bull ant, Myrmecia
RT gulosa, reveals a hyperdiverse hymenopteran toxin gene family.";
RL Sci. Adv. 4:EAAU4640-EAAU4640(2018).
CC -!- FUNCTION: May have antimicrobial properties, like most ant linear
CC peptides. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:30214940}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:30214940}.
CC -!- SIMILARITY: Belongs to the formicidae venom precursor-01 superfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC (NCBI);
CC URL="https://www.ncbi.nlm.nih.gov/nuccore/GGFG01000013";
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; P0DSK6; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Antimicrobial; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT PROPEP 21..44
FT /evidence="ECO:0000305|PubMed:30214940"
FT /id="PRO_0000447098"
FT CHAIN 45..111
FT /note="U-myrmeciitoxin(01)-Mg8b"
FT /evidence="ECO:0000305|PubMed:30214940"
FT /id="PRO_0000447099"
SQ SEQUENCE 111 AA; 11897 MW; 99A83D3250D1B746 CRC64;
MKLSTILVAF VLLIITVILS TPSTNAKALA ESNALAVADP EAEPWLGALF SFIRFIAPYV
IKAIRFVVQV ASKLVKPAKA AIKFAKNIAK DIAEDMAMDF AMDVITGGDD E