TX19A_MYRGU
ID TX19A_MYRGU Reviewed; 79 AA.
AC P0DSK7;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 08-MAY-2019, sequence version 1.
DT 25-MAY-2022, entry version 5.
DE RecName: Full=U-myrmeciitoxin(01)-Mg9a {ECO:0000305};
DE Short=MIITX(01)-Mg9a {ECO:0000303|PubMed:30214940};
DE Short=U-MIITX(01)-Mg9a {ECO:0000305};
DE Flags: Precursor;
OS Myrmecia gulosa (Red bulldog ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmeciinae; Myrmeciini; Myrmecia.
OX NCBI_TaxID=36170;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], MASS SPECTROMETRY, AMIDATION AT GLN-78, AND
RP SUBCELLULAR LOCATION.
RC TISSUE=Venom, and Venom gland;
RX PubMed=30214940; DOI=10.1126/sciadv.aau4640;
RA Robinson S.D., Mueller A., Clayton D., Starobova H., Hamilton B.R.,
RA Payne R.J., Vetter I., King G.F., Undheim E.A.B.;
RT "A comprehensive portrait of the venom of the giant red bull ant, Myrmecia
RT gulosa, reveals a hyperdiverse hymenopteran toxin gene family.";
RL Sci. Adv. 4:EAAU4640-EAAU4640(2018).
CC -!- FUNCTION: May have antimicrobial properties, like most ant linear
CC peptides. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30214940}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:30214940}.
CC -!- MASS SPECTROMETRY: Mass=3246.96; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:30214940};
CC -!- SIMILARITY: Belongs to the formicidae venom precursor-01 superfamily.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC (NCBI);
CC URL="https://www.ncbi.nlm.nih.gov/nuccore/GGFG01000014";
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DR AlphaFoldDB; P0DSK7; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Amidation; Antimicrobial; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..48
FT /evidence="ECO:0000305|PubMed:30214940"
FT /id="PRO_0000447100"
FT PEPTIDE 49..78
FT /note="U-myrmeciitoxin(01)-Mg9a"
FT /evidence="ECO:0000269|PubMed:30214940"
FT /id="PRO_0000447101"
FT MOD_RES 78
FT /note="Glutamine amide"
FT /evidence="ECO:0000269|PubMed:30214940"
SQ SEQUENCE 79 AA; 8252 MW; 3C4AD7194FA1C84C CRC64;
MKLSCLLLTL AIIFVLTIVH APNVEAKALA NPESDAIGFA DAVGEADPNI KWSKYAKKVG
KVIVKHGIPL AASIALSQG