TX22E_PLETR
ID TX22E_PLETR Reviewed; 24 AA.
AC P36987;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=U1-plectoxin-Pt1e {ECO:0000305};
DE Short=U1-PLTX-Pt1e {ECO:0000305};
DE AltName: Full=Plectoxin XIII;
DE Short=PLT-XIII;
DE Short=PLTXIII;
DE AltName: Full=Plectoxin-13;
DE Flags: Fragment;
OS Plectreurys tristis (Spider) (Plectreurys bispinosus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC Araneomorphae; Haplogynae; Pholcoidea; Plectreuridae; Plectreurys.
OX NCBI_TaxID=33319;
RN [1]
RP PROTEIN SEQUENCE, AND SUBCELLULAR LOCATION.
RC TISSUE=Venom;
RX PubMed=8157635; DOI=10.1016/s0021-9258(19)78096-x;
RA Quistad G.B., Skinner W.S.;
RT "Isolation and sequencing of insecticidal peptides from the primitive
RT hunting spider, Plectreurys tristis (Simon).";
RL J. Biol. Chem. 269:11098-11101(1994).
CC -!- FUNCTION: Potent toxin that may paralyze and/or kill insect pests such
CC as H.virescens (lepidoptera), S.exigua (beet armyworm) and M.sexta
CC (tobacco hornworm).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8157635}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:8157635}.
CC -!- PTM: Contains 5 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the neurotoxin 02 (plectoxin) family. 02
CC (plectoxin) subfamily. {ECO:0000305}.
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DR PIR; E53613; E53613.
DR AlphaFoldDB; P36987; -.
DR ArachnoServer; AS000394; U1-plectoxin-Pt1e.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Neurotoxin; Secreted; Toxin.
FT CHAIN 1..>24
FT /note="U1-plectoxin-Pt1e"
FT /evidence="ECO:0000269|PubMed:8157635"
FT /id="PRO_0000087659"
FT DISULFID 4..18
FT /evidence="ECO:0000250|UniProtKB:P83559"
FT DISULFID 17..?
FT /evidence="ECO:0000250|UniProtKB:P83559"
FT DISULFID 21..?
FT /evidence="ECO:0000250|UniProtKB:P83559"
FT NON_TER 24
FT /evidence="ECO:0000305|PubMed:8157635"
SQ SEQUENCE 24 AA; 2745 MW; F74A6889E80B0A9A CRC64;
ALKCQGWVDY CNGNVECCNE CVMY