ID   TX29A_PHOKE             Reviewed;          38 AA.
AC   P84013;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=U9-ctenitoxin-Pk1a;
DE            Short=U9-CNTX-Pk1a;
DE   AltName: Full=Venom protein PKTx22C1;
DE   Flags: Fragment;
OS   Phoneutria keyserlingi (Brazilian wandering spider) (Ctenus keyserlingii).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae;
OC   Araneomorphae; Entelegynae; Lycosoidea; Ctenidae; Phoneutria.
OX   NCBI_TaxID=272754;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Venom {ECO:0000269|PubMed:16278100};
RX   PubMed=16278100; DOI=10.1016/j.cbpc.2005.09.010;
RA   Richardson M., Pimenta A.M., Bemquerer M.P., Santoro M.M., Beirao P.S.,
RA   Lima M.E., Figueiredo S.G., Bloch C. Jr., Vasconcelos E.A., Campos F.A.,
RA   Gomes P.C., Cordeiro M.N.;
RT   "Comparison of the partial proteomes of the venoms of Brazilian spiders of
RT   the genus Phoneutria.";
RL   Comp. Biochem. Physiol. 142:173-187(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16278100}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000269|PubMed:16278100}.
CC   -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC       structurally defines this protein as a knottin. {ECO:0000250}.
CC   -!- MASS SPECTROMETRY: Mass=4734.4; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:16278100};
CC   -!- SIMILARITY: Belongs to the neurotoxin 02 (plectoxin) family. 09
CC       subfamily.
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DR   AlphaFoldDB; P84013; -.
DR   SMR; P84013; -.
DR   ArachnoServer; AS000235; U9-ctenitoxin-Pk1a.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Knottin; Secreted.
FT   CHAIN           1..>38
FT                   /note="U9-ctenitoxin-Pk1a"
FT                   /id="PRO_0000087644"
FT   DISULFID        2..17
FT                   /evidence="ECO:0000250"
FT   DISULFID        9..22
FT                   /evidence="ECO:0000250"
FT   DISULFID        16..36
FT                   /evidence="ECO:0000250"
FT   DISULFID        24..34
FT                   /evidence="ECO:0000250"
FT   NON_TER         38
FT                   /evidence="ECO:0000303|PubMed:16278100"
SQ   SEQUENCE   38 AA;  4542 MW;  196BE5B9AB00C146 CRC64;
     ECIGHRRSCK EDRNGCCKLY TCNCWYPTPD DQWCKCLL